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10.1073/pnas.1505207112 http://scihub22266oqcxt.onion/10.1073/pnas.1505207112 C4577154!4577154!26324897     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=26324897&cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Proc+Natl+Acad+Sci+U+S+A 2015 ; 112 (37): 11654-9 Nephropedia Template TP {{tp|p=26324897|t=2015. Competitive exclusion by autologous antibodies can prevent broad HIV-1 antibodies from arising |pdf=|usr=}}{{26324897}} gab.com Text Competitive exclusion by autologous antibodies can prevent broad HIV-1 antibodies from arising JO: Proc Natl Acad Sci U S A http://www.kidney.de/pget.php?&tw=1&pmid=26324897 #FOAvip Broadly neutralizing antibodies against HIV have recently been discovered, but their highly mutated nature and late emergence in infection make it difficult to infer how they arose. As a step to understanding their development, we investigate antibody?virus coevolution, using a mathematical model. Here we find that broadly neutralizing antibodies in principle may arise earlier and be less mutated, but that competition between broad responses and initial autologous antibody responses delays their emergence. It may be possible to reduce this competition and elicit broadly neutralizing antibodies earlier than previously thought by using a vaccine with diverse viral strains. Twit Text FOAVip Competitive exclusion by autologous antibodies can prevent broad HIV-1 antibodies from arising ????Proc Natl Acad Sci U S A http://www.kidney.de/pget.php?&tw=1&pmid=26324897 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=26324897 #FOAvip English Wikipedia <ref>{{Cite pmid|26324897}}</ref> Competitive exclusion by autologous antibodies can prevent broad HIV-1 antibodies from arising #MMPMID26324897 Luo S; Perelson AS Proc Natl Acad Sci U S A 2015[Sep]; 112 (37): 11654-9 PMID26324897show ga Broadly neutralizing antibodies against HIV have recently been discovered, but their highly mutated nature and late emergence in infection make it difficult to infer how they arose. As a step to understanding their development, we investigate antibody?virus coevolution, using a mathematical model. Here we find that broadly neutralizing antibodies in principle may arise earlier and be less mutated, but that competition between broad responses and initial autologous antibody responses delays their emergence. It may be possible to reduce this competition and elicit broadly neutralizing antibodies earlier than previously thought by using a vaccine with diverse viral strains. äCompetitive exclusion by autologous antibodies can prevent broad HIV-1(epmc).pdf DeepDyve Pubget Overpricing