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2009 ; 34
(5
): 561-5
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Defining cancer risk in dermatomyositis Part II Assessing diagnostic usefulness
of myositis serology
#MMPMID19508476
Madan V
; Chinoy H
; Griffiths CE
; Cooper RG
Clin Exp Dermatol
2009[Jul]; 34
(5
): 561-5
PMID19508476
show ga
In part 1 of this review, we examined the evidence behind the association between
idiopathic inflammatory myopathies (IIM) and cancers. In view of the
well-recognized association between cancer and myositis (hence the term
cancer-associated myositis, or CAM), clinicians responsible for the management of
patients with myositis must make important decisions regarding how intensively
they undertake searches for malignancy. Clinicians must also decide how often
such searches are repeated, and again how intensively, to optimize both cancer
detection and treatment, and thus patient survival. As the risks of CAM are
greatest in dermatomyositis, this is an issue of obvious importance to
dermatologists. In this second of two reviews, we examine the role of
autoantibodies as potential predictors of cancer risk in patients with IIM.