Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=26448897
&cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests
in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215
Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 265.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 265.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 265.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 265.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\26448897
.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117 J+Blood+Transfus
2015 ; 2015
(ä): 874920
Nephropedia Template TP
gab.com Text
Twit Text FOAVip
Twit Text #
English Wikipedia
CRASH-2 Study of Tranexamic Acid to Treat Bleeding in Trauma Patients: A
Controversy Fueled by Science and Social Media
#MMPMID26448897
Binz S
; McCollester J
; Thomas S
; Miller J
; Pohlman T
; Waxman D
; Shariff F
; Tracy R
; Walsh M
J Blood Transfus
2015[]; 2015
(ä): 874920
PMID26448897
show ga
This paper reviews the application of tranexamic acid, an antifibrinolytic, to
trauma. CRASH-2, a large randomized controlled trial, was the first to show a
reduction in mortality and recommend tranexamic acid use in bleeding trauma
patients. However, this paper was not without controversy. Its patient
recruitment, methodology, and conductance in moderate-to-low income countries
cast doubt on its ability to be applied to trauma protocols in countries with
mature trauma networks. In addition to traditional vetting in scientific,
peer-reviewed journals, CRASH-2 came about at a time when advances in
communication technology allowed debate and influence to be leveraged in new
forms, specifically through the use of multimedia campaigns, social media, and
Internet blogs. This paper presents a comprehensive view of tranexamic acid
utilization in trauma from peer-reviewed evidence to novel multimedia influences.