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Accuracy of Venous Filling Index on Standing (VFIst) and Pure Regurgitation Index
(PRI), a Novel Index Obtained by Air Plethysmography, for Detecting Venous
Reflux
#MMPMID26421073
Shiraishi Y
Ann Vasc Dis
2015[]; 8
(3
): 236-41
PMID26421073
show ga
OBJECTIVE: To evaluate the accuracy of venous filling index on standing (VFIst)
and a new index named pure regurgitation index (PRI), obtained by air
plethysmography, for detecting venous reflux. MATERIALS AND METHODS: One hundred
and sixty-one healthy subjects (161 limbs) and 180 varicose vein patients (180
limbs) were investigated. All subjects underwent duplex ultrasonography for
verifying venous reflux and air plethysmography to obtain hemodynamic parameters
such as VFIst, VFI in the supine position (VFIsu), and the maximum arterial
inflow rate. To evaluate the accuracy of VFIst and PRI (= (VFIst - VFIsu)/body
mass index), receiver operating characteristics curves were created. RESULTS: The
optimal cut-off value, sensitivity, specificity, and area under the curve,
obtained from analyzing the receiver operating characteristics curves, of VFIst
vs. PRI were 2.058 mL/s vs. 0.059 mL · m(2)/s · kg, 93.3% vs. 90.3%, 88.8% vs.
91.3%, and 0.954 vs. 0.964, respectively. CONCLUSIONS: This study indicates that
while both VFIst and PRI are highly accurate indicators of venous reflux, PRI,
which is not affected by the arterial inflow rate and body mass index, is
slightly superior to VFIst, especially in subjects with greater body mass index.