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10.1007/s13300-015-0126-y http://scihub22266oqcxt.onion/10.1007/s13300-015-0126-y C4575298!4575298!26238041     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Diabetes+Ther 2015 ; 6 (3): 389-93 Nephropedia Template TP {{tp|p=26238041|t=2015. Investigating the Evidence of the Real-Life Impact of Acute Hyperglycaemia |pdf=|usr=}}{{26238041}} gab.com Text Investigating the Evidence of the Real-Life Impact of Acute Hyperglycaemia JO: Diabetes Ther http://www.kidney.de/pget.php?&tw=1&pmid=26238041 #FOAvip Abstract: Poorly controlled diabetes mellitus (DM) is associated with the development of long-term micro- and macro-vascular complications. The predominant focus of anti-diabetic therapy has been on lowering glycosylated haemoglobin levels, with a strong emphasis on fasting plasma glucose (particularly in Type 2 DM). There is considerable evidence indicating that post-meal hyperglycaemic levels are independently associated with higher risks of macro-vascular disease. Although some have identified mechanisms which may account for these observations, interventions which have specifically targeted postprandial glucose rises showed little or no effect in reducing cardiovascular risk. Clinical experience and some recent studies suggest acute hyperglycaemia affects cognition and other indicators of performance, equivalent to impairment seen during hypoglycaemia. In this brief report, we evaluated the published studies and argue that acute hyperglycaemia is worth investigating in relation to the real-life implications. In summary, evidence exists suggesting that acute hyperglycaemia may lead to impaired cognitive performance and productivity, but the relationship between these effects and daily activities remains poorly understood. Further research is required to enhance our understanding of acute hyperglycaemia in daily life. A better appreciation of clinically relevant effects of acute hyperglycaemia will allow us to determine whether it needs to be addressed by specific treatment. Funding: Novo Nordisk A/S Søborg, Denmark. Electronic supplementary material: The online version of this article (doi:10.1007/s13300-015-0126-y) contains supplementary material, which is available to authorized users. Twit Text FOAVip Investigating the Evidence of the Real-Life Impact of Acute Hyperglycaemia ????Diabetes Ther http://www.kidney.de/pget.php?&tw=1&pmid=26238041 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=26238041 #FOAvip English Wikipedia <ref>{{Cite pmid|26238041}}</ref> Investigating the Evidence of the Real-Life Impact of Acute Hyperglycaemia #MMPMID26238041 Heller S; Houwing N; Kragh N; Ploug UJ; Nikolajsen A; Alleman CJM Diabetes Ther 2015[Sep]; 6 (3): 389-93 PMID26238041show ga Abstract: Poorly controlled diabetes mellitus (DM) is associated with the development of long-term micro- and macro-vascular complications. The predominant focus of anti-diabetic therapy has been on lowering glycosylated haemoglobin levels, with a strong emphasis on fasting plasma glucose (particularly in Type 2 DM). There is considerable evidence indicating that post-meal hyperglycaemic levels are independently associated with higher risks of macro-vascular disease. Although some have identified mechanisms which may account for these observations, interventions which have specifically targeted postprandial glucose rises showed little or no effect in reducing cardiovascular risk. Clinical experience and some recent studies suggest acute hyperglycaemia affects cognition and other indicators of performance, equivalent to impairment seen during hypoglycaemia. In this brief report, we evaluated the published studies and argue that acute hyperglycaemia is worth investigating in relation to the real-life implications. In summary, evidence exists suggesting that acute hyperglycaemia may lead to impaired cognitive performance and productivity, but the relationship between these effects and daily activities remains poorly understood. Further research is required to enhance our understanding of acute hyperglycaemia in daily life. A better appreciation of clinically relevant effects of acute hyperglycaemia will allow us to determine whether it needs to be addressed by specific treatment. Funding: Novo Nordisk A/S Søborg, Denmark. Electronic supplementary material: The online version of this article (doi:10.1007/s13300-015-0126-y) contains supplementary material, which is available to authorized users. äInvestigating the Evidence of the Real-Life Impact of Acute Hyperglyca(epmc).pdf DeepDyve Pubget Overpricing