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10.1111/j.1365-2796.2012.02556.x http://scihub22266oqcxt.onion/10.1111/j.1365-2796.2012.02556.x C4573524!4573524!22640224     free     free     free Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       J+Intern+Med 2012 ; 272 (2): 144-57 Nephropedia Template TP {{tp|p=22640224|t=2012. Allergen-specific immunotherapy: from therapeutic vaccines to prophylactic approaches |pdf=|usr=}}{{22640224}} gab.com Text Allergen-specific immunotherapy: from therapeutic vaccines to prophylactic approaches JO: J Intern Med http://www.kidney.de/pget.php?&tw=1&pmid=22640224 #FOAvip Immunoglobulin E-mediated allergies affect more than 25% of the population. Allergen exposure induces a variety of symptoms in allergic patients, which include rhinitis, conjunctivitis, asthma, dermatitis, food allergy and life-threatening systemic anaphylaxis. At present, allergen-specific immunotherapy (SIT), which is based on the administration of the disease-causing allergens, is the only disease-modifying treatment for allergy. Current therapeutic allergy vaccines are still prepared from relatively poorly defined allergen extracts. However, with the availability of the structures of the most common allergen molecules, it has become possible to produce well-defined recombinant and synthetic allergy vaccines that allow specific targeting of the mechanisms of allergic disease. Here we provide a summary of the development and mechanisms of SIT, and then review new forms of therapeutic vaccines that are based on recombinant and synthetic molecules. Finally, we discuss possible allergen-specific strategies for prevention of allergic disease. Twit Text FOAVip Allergen-specific immunotherapy: from therapeutic vaccines to prophylactic approaches ????J Intern Med http://www.kidney.de/pget.php?&tw=1&pmid=22640224 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=22640224 #FOAvip English Wikipedia <ref>{{Cite pmid|22640224}}</ref> Allergen-specific immunotherapy: from therapeutic vaccines to prophylactic approaches #MMPMID22640224 Valenta R; Campana R; Marth K; van Hage M J Intern Med 2012[Aug]; 272 (2): 144-57 PMID22640224show ga Immunoglobulin E-mediated allergies affect more than 25% of the population. Allergen exposure induces a variety of symptoms in allergic patients, which include rhinitis, conjunctivitis, asthma, dermatitis, food allergy and life-threatening systemic anaphylaxis. At present, allergen-specific immunotherapy (SIT), which is based on the administration of the disease-causing allergens, is the only disease-modifying treatment for allergy. Current therapeutic allergy vaccines are still prepared from relatively poorly defined allergen extracts. However, with the availability of the structures of the most common allergen molecules, it has become possible to produce well-defined recombinant and synthetic allergy vaccines that allow specific targeting of the mechanisms of allergic disease. Here we provide a summary of the development and mechanisms of SIT, and then review new forms of therapeutic vaccines that are based on recombinant and synthetic molecules. Finally, we discuss possible allergen-specific strategies for prevention of allergic disease. äAllergen-specific immunotherapy: from therapeutic vaccines to prophyla(epmc).pdf DeepDyve Pubget Overpricing