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2015 ; 24
(3
): 198-204
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Intravascular Near-Infrared Spectroscopy: A Possible Tool for Optimizing the
Management of Carotid Artery Disease
#MMPMID26417188
Horváth M
; Hájek P
; ?t?chovský C
; Hon?k J
; Veselka J
Int J Angiol
2015[Sep]; 24
(3
): 198-204
PMID26417188
show ga
Stroke is the second most common cause of morbidity and mortality in the Western
nations. It is estimated that approximately one-fifth of all strokes or transient
ischemic attacks are caused by carotid artery disease. Thus, treatment of carotid
artery disease as a mean of stroke prevention is extremely important. Since the
introduction of carotid endarterectomy, debate has persisted over the treatment
strategy for carotid artery disease. Current recommendations have many potential
flaws because they are often based on older trials performed before the
introduction of modern pharmacotherapy and are mostly based on the angiographic
degree of stenosis, without an emphasis on the pathophysiology of the disease.
Most carotid events are caused by rupture or distal embolization of the content
of an unstable atherosclerotic plaque with a large lipid pool. Thus, it is
plausible that the information regarding the composition of the atherosclerotic
plaque could play an important role in deciding on a treatment strategy. In this
review article, we provide information about near-infrared spectroscopy, a new
invasive imaging modality, which seems to be capable of providing such
information.