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10.2147/DDDT.S89669

http://scihub22266oqcxt.onion/10.2147/DDDT.S89669
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C4571933!4571933!26388687
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suck abstract from ncbi


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pmid26388687      Drug+Des+Devel+Ther 2015 ; 9 (ä): 5195-201
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  • Pentoxifylline and electromagnetic field improved bone fracture healing in rats #MMPMID26388687
  • Atalay Y; Gunes N; Guner MD; Akpolat V; Celik MS; Guner R
  • Drug Des Devel Ther 2015[]; 9 (ä): 5195-201 PMID26388687show ga
  • Background: The aim of this study was to evaluate the effects of a phosphodiesterase inhibitor pentoxifylline (PTX), electromagnetic fields (EMFs), and a mixture of both materials on bone fracture healing in a rat model. Materials and methods: Eighty male Wistar rats were randomly divided into four groups: Group A, femur fracture model with no treatment; Group B, femur fracture model treated with PTX 50 mg/kg/day intraperitoneal injection; Group C, femur fracture model treated with EMF 1.5±0.2 Mt/50 Hz/6 hours/day; and Group D, femur fracture model treated with PTX 50 mg/kg/day intraperitoneal injection and EMF 1.5±0.2 Mt/50 Hz/6 hours/day. Results: Bone fracture healing was significantly better in Group B and Group C compared to Group A (P<0.05), but Group D did not show better bone fracture healing than Group A (P>0.05). Conclusion: It can be concluded that both a specific EMF and PTX had a positive effect on bone fracture healing but when used in combination, may not be beneficial.
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