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10.1007/s13139-014-0284-2

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suck abstract from ncbi


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pmid26396630      Nucl+Med+Mol+Imaging 2014 ; 48 (4): 262-71
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  • Tc-99m Hydroxymethylene Diphosphonate (HMDP) Renal Uptake as a Surrogate Marker of Postoperative Impairment of the Glomerular Filtration Rate in Renal Tumor Patients Following Nephron-Sparing Surgery #MMPMID26396630
  • Choi H; Lee WW; So Y; Ha S; Byun SS; Kim SE
  • Nucl Med Mol Imaging 2014[Dec]; 48 (4): 262-71 PMID26396630show ga
  • Purpose: We investigated Tc-99m hydroxymethylene diphosphonate (HMDP) scintigraphy findings in renal tumor patients from the perspective of postoperative renal dysfunction following nephron-sparing surgery (NSS). Methods: Forty-three renal tumor patients (M:F = 28:15, age 53.9?±?12.5 years) who had undergone Tc-99m HMDP scintigraphy after NSS were enrolled. The patients were divided into HMDP+ or HMDP? groups by visual assessment, and the asymmetric index (ASI) was calculated using a region-of-interest analysis. In 16 patients, the total and split glomerular filtration rate (GFR) was assessed using Tc-99m diethylenetriaminepentaacetic acid (DTPA) scintigraphy at baseline and at 3 and 6 months post-NSS. Results: High Tc-99m HMDP uptake was observed in the operated kidneys, but this did not persist later than 7 days post-NSS. Split GFR of the operated kidneys at baseline (58.5?±?9.3 ml/min) was significantly reduced at 6 months post-NSS (40.1?±?5.9 ml/min, p?
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