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10.1093/imammb/dqt003 http://scihub22266oqcxt.onion/10.1093/imammb/dqt003 C4571485!4571485!23518337     free     free     free Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Math+Med+Biol 2014 ; 31 (2): 179-204 Nephropedia Template TP {{tp|p=23518337|t=2014. Mathematical modelling of Pseudomonas aeruginosa biofilm growth and treatment in the cystic fibrosis lung |pdf=|usr=}}{{23518337}} gab.com Text Mathematical modelling of Pseudomonas aeruginosa biofilm growth and treatment in the cystic fibrosis lung JO: Math Med Biol http://www.kidney.de/pget.php?&tw=1&pmid=23518337 #FOAvip Lung failure due to chronic bacterial infection is the leading cause of death for patients with cystic fibrosis (CF). It is thought that the chronic nature of these infections is, in part, due to the increased tolerance and recalcitrant behaviour of bacteria growing as biofilms. Inhalation of silver carbene complex (SCC) antimicrobial, either encased in polymeric biodegradable particles or in aqueous form, has been proposed as a treatment. Through a coordinated experimental and mathematical modelling effort, we examine this proposed treatment of lung biofilms. Pseudomonas aeruginosa biofilms grown in a flow-cell apparatus irrigated with an artificial CF sputum medium are analysed as an in vitro model of CF lung infection. A 2D mathematical model of biofilm growth within the flow-cell is developed. Numerical simulations demonstrate that SCC inactivation by the environment is critical in aqueous SCC, but not SCC-polymer, based treatments. Polymer particle degradation rate is shown to be an important parameter that can be chosen optimally, based on environmental conditions and bacterial susceptibility. Twit Text FOAVip Mathematical modelling of Pseudomonas aeruginosa biofilm growth and treatment in the cystic fibrosis lung ????Math Med Biol http://www.kidney.de/pget.php?&tw=1&pmid=23518337 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=23518337 #FOAvip English Wikipedia <ref>{{Cite pmid|23518337}}</ref> Mathematical modelling of Pseudomonas aeruginosa biofilm growth and treatment in the cystic fibrosis lung #MMPMID23518337 Miller JK; Brantner JS; Clemons C; Kreider KL; Milsted A; Wilber P; Yun YH; Youngs WJ; Young G; Badawy HT; Milsted A; Clemons C; Kreider KL; Wilber P; Young G; Yun YH; Wagers PO; Youngs WJ Math Med Biol 2014[Jun]; 31 (2): 179-204 PMID23518337show ga Lung failure due to chronic bacterial infection is the leading cause of death for patients with cystic fibrosis (CF). It is thought that the chronic nature of these infections is, in part, due to the increased tolerance and recalcitrant behaviour of bacteria growing as biofilms. Inhalation of silver carbene complex (SCC) antimicrobial, either encased in polymeric biodegradable particles or in aqueous form, has been proposed as a treatment. Through a coordinated experimental and mathematical modelling effort, we examine this proposed treatment of lung biofilms. Pseudomonas aeruginosa biofilms grown in a flow-cell apparatus irrigated with an artificial CF sputum medium are analysed as an in vitro model of CF lung infection. A 2D mathematical model of biofilm growth within the flow-cell is developed. Numerical simulations demonstrate that SCC inactivation by the environment is critical in aqueous SCC, but not SCC-polymer, based treatments. Polymer particle degradation rate is shown to be an important parameter that can be chosen optimally, based on environmental conditions and bacterial susceptibility. äMathematical modelling of Pseudomonas aeruginosa biofilm growth and tr(epmc).pdf DeepDyve Pubget Overpricing