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10.1091/mbc.E15-02-0074

http://scihub22266oqcxt.onion/10.1091/mbc.E15-02-0074
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C4571326!4571326!26108623
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suck abstract from ncbi


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pmid26108623      Mol+Biol+Cell 2015 ; 26 (16): 2873-84
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  • Ire1-mediated decay in mammalian cells relies on mRNA sequence, structure, and translational status #MMPMID26108623
  • Moore K; Hollien J
  • Mol Biol Cell 2015[Aug]; 26 (16): 2873-84 PMID26108623show ga
  • Endoplasmic reticulum (ER) stress induces the degradation of mRNAs by Ire1. In mammalian cells, this process depends on specific stem-loop structures in the target mRNAs and on Perk, a second sensor of ER stress. Perk appears to be required to translationally attenuate the stem-loop regions of target mRNAs.
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