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.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117 J+Orthop+Surg+Res
2015 ; 10
(ä): 122
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Meta-analysis of locking plate versus intramedullary nail for treatment of
proximal humeral fractures
#MMPMID26370230
Wang G
; Mao Z
; Zhang L
; Zhang L
; Zhao Y
; Yin P
; Gao L
; Tang P
; Kang H
J Orthop Surg Res
2015[Sep]; 10
(ä): 122
PMID26370230
show ga
PURPOSE: This meta-analysis compared the clinical outcomes of locking plate with
intramedullary nail in the treatment of displaced proximal humeral fractures.
METHODS: We searched PubMed, Embase, and the Cochrane databases for studies
comparing locking plate and intramedullary nail treatment of displaced two-,
three-, or four-part proximal humeral fractures. The quality of the studies was
assessed, and meta-analysis was performed using the Cochrane Collaboration's
REVMAN 5.1 software. RESULTS: A total of 615 patients from eight studies were
included in this meta-analysis (348 fractures treated with locking plate and 267
with intramedullary nail). Similar Constant scores were observed between the
locking plate and intramedullary nail both in randomized controlled trials (RCTs)
(mean difference (MD)?=?2.12, 95% confidence interval (CI), -2.54 to 6.79,
P?=?0.37) and observational studies (MD?=?-1.93, 95% CI, -4.95 to 1.09,
P?=?0.21). Only one RCT provided American Shoulder and Elbow Surgeons
Standardized scores indicating that the locking plate was better than the
intramedullary nail (MD?=?7.20, 95% CI, 1.29-13.11, P?=?0.02). The total
complication rate did not specifically favor the locking plate or intramedullary
nail both in the RCTs (risk ratio (RR), 2.44; 95% CI, 0.35-16.78; P?=?0.37) and
observational studies (RR, 1.01; 95% CI, 0.72-1.43; P?=?0.94). CONCLUSIONS: In
the existing literature, limited evidence suggests that the locking plate and
intramedullary nail are both valuable options for the treatment of proximal
humeral fractures. Because of the observed heterogeneity and variance between the
subgroups, more RCT are needed to be able to definitively recommend a locking
plate or intramedullary nail for specific fracture patterns.