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10.1117/1.3528593 http://scihub22266oqcxt.onion/10.1117/1.3528593 C4570115!4570115 !21280909     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=21280909 &cmd=llinks): Failed to open stream: HTTP request failed! 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Two-dimensional singlet oxygen imaging with its near-infrared luminescence during photosensitization |pdf=|usr=}}{{21280909 }} gab.com Text Two-dimensional singlet oxygen imaging with its near-infrared luminescence during photosensitization JO: J Biomed Opt http://www.kidney.de/pget.php?&tw=1&pmid=21280909 #FOAvip Photodynamic therapy is a promising cancer treatment that involves activation of photosensitizer by visible light to create singlet oxygen. This highly reactive oxygen species is believed to induce cell death and tissue destruction in PDT. Our approach used a near-infrared area CCD with high quantum efficiency to detect singlet oxygen by its 1270-nm luminescence. Two-dimensional singlet oxygen images with its near-infrared luminescence during photosensitization could be obtained with a CCD integration time of 1 s, without scanning. Thus this system can produce singlet oxygen luminescence images faster and achieve more accurate measurements in comparison to raster-scanning methods. The experimental data show a linear relationship between the singlet oxygen luminescence intensity and sample concentration. This method provides a detection sensitivity of 0.0181 ?g?ml (benzoporphyrin derivative monoacid ring A dissolved in ethanol) and a spatial resolution better than 50 ?m. A pilot study was conducted on a total of six female Kunming mice. The results from this study demonstrate the system's potential for in vivo measurements. Further experiments were carried out on two tumor-bearing nude mice. Singlet oxygen luminescence images were acquired from the tumor-bearing nude mouse with intravenous injection of BPD-MA, and the experimental results showed real-time singlet oxygen signal depletion as a function of the light exposure. Twit Text FOAVip Two-dimensional singlet oxygen imaging with its near-infrared luminescence during photosensitization ????J Biomed Opt http://www.kidney.de/pget.php?&tw=1&pmid=21280909 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=21280909 #FOAvip English Wikipedia <ref>{{Cite pmid|21280909 }}</ref> Two-dimensional singlet oxygen imaging with its near-infrared luminescence during photosensitization #MMPMID21280909 Hu B ; Zeng N ; Liu Z ; Ji Y ; Xie W ; Peng Q ; Zhou Y ; He Y ; Ma H J Biomed Opt 2011[Jan]; 16 (1 ): 016003 PMID21280909 show ga Photodynamic therapy is a promising cancer treatment that involves activation of photosensitizer by visible light to create singlet oxygen. This highly reactive oxygen species is believed to induce cell death and tissue destruction in PDT. Our approach used a near-infrared area CCD with high quantum efficiency to detect singlet oxygen by its 1270-nm luminescence. Two-dimensional singlet oxygen images with its near-infrared luminescence during photosensitization could be obtained with a CCD integration time of 1 s, without scanning. Thus this system can produce singlet oxygen luminescence images faster and achieve more accurate measurements in comparison to raster-scanning methods. The experimental data show a linear relationship between the singlet oxygen luminescence intensity and sample concentration. This method provides a detection sensitivity of 0.0181 ?g?ml (benzoporphyrin derivative monoacid ring A dissolved in ethanol) and a spatial resolution better than 50 ?m. A pilot study was conducted on a total of six female Kunming mice. The results from this study demonstrate the system's potential for in vivo measurements. Further experiments were carried out on two tumor-bearing nude mice. Singlet oxygen luminescence images were acquired from the tumor-bearing nude mouse with intravenous injection of BPD-MA, and the experimental results showed real-time singlet oxygen signal depletion as a function of the light exposure. |Animals [MESH] |Cell Line, Tumor [MESH] |Female [MESH] |Infrared Rays [MESH] |Luminescent Measurements/*methods [MESH] |Male [MESH] |Mice [MESH] |Mice, Nude [MESH] |Neoplasms, Experimental/*drug therapy/*metabolism/pathology [MESH] |Photosensitizing Agents/*therapeutic use [MESH] |Porphyrins/*therapeutic use [MESH] |Singlet Oxygen/*analysis [MESH]Two-dimensional singlet oxygen imaging with its near-infrared luminesc(epmc).pdf DeepDyve Pubget Overpricing