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10.1080/2162402X.2015.1036214

http://scihub22266oqcxt.onion/10.1080/2162402X.2015.1036214
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C4570113!4570113!26405604
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suck abstract from ncbi


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pmid26405604      Oncoimmunology 2015 ; 4 (9): ä
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  • The checkpoint inhibitor TIGIT limits antitumor and antiviral CD8+ T cell responses #MMPMID26405604
  • Johnston RJ; Yu X; Grogan JL
  • Oncoimmunology 2015[Sep]; 4 (9): ä PMID26405604show ga
  • Success in eliciting tumor rejection by therapeutic blockade of T cell checkpoint inhibitors, such as PD-1/PD-L1 and CTLA-4, has spurred re-evaluation of additional receptors that regulate antitumor responses. Here we summarize our recent studies characterizing the role of co-inhibitory receptor TIGIT in antitumor and other chronic CD8+ T cell responses.
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