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2015 ; 10
(9
): e0137962
Nephropedia Template TP
gab.com Text
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English Wikipedia
Safe Corridor to Access Clivus for Endoscopic Trans-Sphenoidal Surgery: A
Radiological and Anatomical Study
#MMPMID26368821
Cheng Y
; Zhang S
; Chen Y
; Zhao G
PLoS One
2015[]; 10
(9
): e0137962
PMID26368821
show ga
PURPOSE: Penetration of the clivus is required for surgical access of the brain
stem. The endoscopic transclivus approach is a difficult procedure with high risk
of injury to important neurovascular structures. We undertook a novel anatomical
and radiological investigation to understand the structure of the clivus and
neurovascular structures relevant to the extended trans-nasal trans-sphenoid
procedure and determine a safe corridor for the penetration of the clivus.
METHOD: We examined the clivus region in the computed tomographic angiography
(CTA) images of 220 adults, magnetic resonance (MR) images of 50 adults, and dry
skull specimens of 10 adults. Multiplanar reconstruction (MPR) of the CT images
was performed, and the anatomical features of the clivus were studied in the
coronal, sagittal, and axial planes. The data from the images were used to
determine the anatomical parameters of the clivus and neurovascular structures,
such as the internal carotid artery and inferior petrosal sinus. RESULTS: The
examination of the CTA and MR images of the enrolled subjects revealed that the
thickness of the clivus helped determine the depth of the penetration, while the
distance from the sagittal midline to the important neurovascular structures
determined the width of the penetration. Further, data from the CTA and MR images
were consistent with those retrieved from the examination of the cadaveric
specimens. CONCLUSION: Our findings provided certain pointers that may be useful
in guiding the surgery such that inadvertent injury to vital structures is
avoided and also provided supportive information for the choice of the
appropriate endoscopic equipment.