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10.1016/j.clinthera.2015.02.014 http://scihub22266oqcxt.onion/10.1016/j.clinthera.2015.02.014 C4568741!4568741!25773457     free     free     free Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 243.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Clin+Ther 2015 ; 37 (3): 505-14 Nephropedia Template TP {{tp|p=25773457|t=2015. Salivary cortisol results obtainable within minutes of sample collection correspond with traditional immunoassays |pdf=|usr=}}{{25773457}} gab.com Text Salivary cortisol results obtainable within minutes of sample collection correspond with traditional immunoassays JO: Clin Ther http://www.kidney.de/pget.php?&tw=1&pmid=25773457 #FOAvip Purpose: Cortisol is frequently assayed as a stress-responsive biomarker which changes over the course of minutes to meet the demands of an individual?s social context. Salivary cortisol is often utilized as a non-invasive sampling methodology which possesses important health implications. A critical barrier to psychobiological research involving salivary cortisol is a time-delay of days to months before cortisol results are obtained via immunoassay, long after the individual is no longer proximate to the social context in which they provided the sample. The current study was designed to address this critical barrier through creation of a lateral flow technology (LFT) cortisol device capable of measuring salivary cortisol within minutes of sample collection. LFT is frequently used within commercial point-of-care settings to obtain rapid answers to the presence/absence of a biomarker. The present study extends LFT into the research domain by presenting performance characteristics of a quantitative LFT which measures salivary cortisol within 20 minutes of sample collection. Methods: Saliva samples on N=29 adults (15 males) were obtained in the morning and afternoon using Passive Drool and then the Super?SAL? Extra Collection Device (hereafter Super?SAL?) and later assayed with LFT and a commercially available enzyme-immunoassay. Findings: Results show LFT correlated well with these collection methods (R=.872 with Super?SAL?; R=.739 with Passive Drool, p-values<.0001) and at comparable levels to correspondence of Super?SAL? with Passive Drool (R=.798, p<.0001) which were measured with the same assay. Implications: These results open up an exciting new possibility to integrate this technological advance into stress research, including knowing and potentially changing the individual?s social context in a time-sensitive manner. Methodological improvements such as this have the possibility of refining conceptual models of stress reactivity and regulation. Twit Text FOAVip Salivary cortisol results obtainable within minutes of sample collection correspond with traditional immunoassays ????Clin Ther http://www.kidney.de/pget.php?&tw=1&pmid=25773457 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=25773457 #FOAvip English Wikipedia <ref>{{Cite pmid|25773457}}</ref> Salivary cortisol results obtainable within minutes of sample collection correspond with traditional immunoassays #MMPMID25773457 Shirtcliff E; Buck R; Laughlin M; Hart T; Cole C; Slowey P Clin Ther 2015[Mar]; 37 (3): 505-14 PMID25773457show ga Purpose: Cortisol is frequently assayed as a stress-responsive biomarker which changes over the course of minutes to meet the demands of an individual?s social context. Salivary cortisol is often utilized as a non-invasive sampling methodology which possesses important health implications. A critical barrier to psychobiological research involving salivary cortisol is a time-delay of days to months before cortisol results are obtained via immunoassay, long after the individual is no longer proximate to the social context in which they provided the sample. The current study was designed to address this critical barrier through creation of a lateral flow technology (LFT) cortisol device capable of measuring salivary cortisol within minutes of sample collection. LFT is frequently used within commercial point-of-care settings to obtain rapid answers to the presence/absence of a biomarker. The present study extends LFT into the research domain by presenting performance characteristics of a quantitative LFT which measures salivary cortisol within 20 minutes of sample collection. Methods: Saliva samples on N=29 adults (15 males) were obtained in the morning and afternoon using Passive Drool and then the Super?SAL? Extra Collection Device (hereafter Super?SAL?) and later assayed with LFT and a commercially available enzyme-immunoassay. Findings: Results show LFT correlated well with these collection methods (R=.872 with Super?SAL?; R=.739 with Passive Drool, p-values<.0001) and at comparable levels to correspondence of Super?SAL? with Passive Drool (R=.798, p<.0001) which were measured with the same assay. Implications: These results open up an exciting new possibility to integrate this technological advance into stress research, including knowing and potentially changing the individual?s social context in a time-sensitive manner. Methodological improvements such as this have the possibility of refining conceptual models of stress reactivity and regulation. äSalivary cortisol results obtainable within minutes of sample collecti(epmc).pdf DeepDyve Pubget Overpricing