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10.1016/j.jcf.2015.05.009 http://scihub22266oqcxt.onion/10.1016/j.jcf.2015.05.009 C4567928!4567928!26074007     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 245.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 245.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       J+Cyst+Fibros 2015 ; 14 (5): 621-6 Nephropedia Template TP {{tp|p=26074007|t=2015. ELECTRONIC MONITORING REVEALS HIGHLY VARIABLE ADHERENCE PATTERNS IN PATIENTS PRESCRIBED IVACAFTOR |pdf=|usr=}}{{26074007}} gab.com Text ELECTRONIC MONITORING REVEALS HIGHLY VARIABLE ADHERENCE PATTERNS IN PATIENTS PRESCRIBED IVACAFTOR JO: J Cyst Fibros http://www.kidney.de/pget.php?&tw=1&pmid=26074007 #FOAvip Background: Previous studies of CF treatments have shown suboptimal adherence, though little has been reported regarding adherence patterns to ivacaftor. Electronic monitoring (EM) of adherence is considered a gold standard of measurement. Methods: Adherence rates by EM were prospectively obtained and patterns over time were analyzed. EM-derived adherence rates were compared to pharmacy refill history and self-report. Results: 12 subjects (age 6-48 years; CFTR-G551D mutation) previously prescribed ivacaftor were monitored for a mean of 118 days. Overall adherence by EM was 61%(SD=28%) and decreased over time. Median duration between doses was 16.9 hours (IQR 13.9-24.1 hours) and increased over time. There was no correlation between EM-derived adherence and either refill history (84%, r=0.26, p=0.42) or self-report (100%, r=0.40, p=0.22). Conclusions: Despite the promising nature of ivacaftor, our data suggest adherence rates are suboptimal and comparable to other prescribed CF therapies, and more commonly used assessments of adherence may be unreliable. Twit Text FOAVip ELECTRONIC MONITORING REVEALS HIGHLY VARIABLE ADHERENCE PATTERNS IN PATIENTS PRESCRIBED IVACAFTOR ????J Cyst Fibros http://www.kidney.de/pget.php?&tw=1&pmid=26074007 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=26074007 #FOAvip English Wikipedia <ref>{{Cite pmid|26074007}}</ref> ELECTRONIC MONITORING REVEALS HIGHLY VARIABLE ADHERENCE PATTERNS IN PATIENTS PRESCRIBED IVACAFTOR #MMPMID26074007 Siracusa CM; Ryan J; Burns L; Wang Y; Zhang N; Clancy JP; Drotar D J Cyst Fibros 2015[Sep]; 14 (5): 621-6 PMID26074007show ga Background: Previous studies of CF treatments have shown suboptimal adherence, though little has been reported regarding adherence patterns to ivacaftor. Electronic monitoring (EM) of adherence is considered a gold standard of measurement. Methods: Adherence rates by EM were prospectively obtained and patterns over time were analyzed. EM-derived adherence rates were compared to pharmacy refill history and self-report. Results: 12 subjects (age 6-48 years; CFTR-G551D mutation) previously prescribed ivacaftor were monitored for a mean of 118 days. Overall adherence by EM was 61%(SD=28%) and decreased over time. Median duration between doses was 16.9 hours (IQR 13.9-24.1 hours) and increased over time. There was no correlation between EM-derived adherence and either refill history (84%, r=0.26, p=0.42) or self-report (100%, r=0.40, p=0.22). Conclusions: Despite the promising nature of ivacaftor, our data suggest adherence rates are suboptimal and comparable to other prescribed CF therapies, and more commonly used assessments of adherence may be unreliable. äELECTRONIC MONITORING REVEALS HIGHLY VARIABLE ADHERENCE PATTERNS IN PA(epmc).pdf DeepDyve Pubget Overpricing