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2015 ; 2015
(ä): ä Nephropedia Template TP
gab.com Text
Twit Text FOAVip
Twit Text #
English Wikipedia
An unusual presentation of Guillain-Barré syndrome in a young man with bilateral
upper extremity weakness
#MMPMID26351312
McNicholas N
; O'Dowd S
; McNamara B
; O'Toole O
BMJ Case Rep
2015[Sep]; 2015
(ä): ä PMID26351312
show ga
A 30-year-old man attended the emergency department with a 4-day history of
progressive, bilateral upper limb weakness. He had mild shortness of breath and
occasional swallowing difficulties. One month prior to presentation, he had
flu-like symptoms and diarrhoea. Examination revealed upper limb hypotonia,
symmetrical distal arm weakness and hyporeflexia. Power and reflexes in the lower
limbs were normal. Nerve conduction studies and lumbar puncture demonstrated
features consistent with Guillain-Barré syndrome (GBS). The patient was treated
with a 5-day course of intravenous immunoglobulins. He improved significantly
over the next 2?weeks. Breathing and swallow function did not deteriorate and
required no further intervention. He had a sustained improvement, and remained at
baseline 1?year later. Work-up for underlying structural, infectious,
inflammatory and paraneoplastic aetiologies were negative. Serum antiganglioside
antibodies were positive for the anti-GT1a IgG isotype supporting the clinical
diagnosis of the pharyngeal-cervical-brachial variant of GBS.