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.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117 PLoS+One
2015 ; 10
(9
): e0137946
Nephropedia Template TP
gab.com Text
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Twit Text #
English Wikipedia
Surgical Clipping versus Endovascular Intervention for the Treatment of
Subarachnoid Hemorrhage Patients in New York State
#MMPMID26360422
Bekelis K
; Missios S
; Coy S
; Rahmani R
; Singer RJ
; MacKenzie TA
PLoS One
2015[]; 10
(9
): e0137946
PMID26360422
show ga
OBJECT: Randomized trials have demonstrated a survival benefit for endovascular
treatment of ruptured cerebral aneurysms. We investigated the association of
surgical clipping and endovascular coiling with outcomes in subarachnoid
hemorrhage (SAH) patients in a real-world regional cohort. METHODS: We performed
a cohort study involving patients with ruptured cerebral aneurysms, who underwent
surgical clipping, or endovascular coiling from 2009-2013 and were registered in
the Statewide Planning and Research Cooperative System (SPARCS) database. An
instrumental variable analysis was used to investigate the association of
treatment technique with outcomes. RESULTS: Of the 4,098 patients undergoing
treatment, 2,585 (63.1%) underwent coiling, and 1,513 (36.9%) underwent clipping.
Using an instrumental variable analysis, we did not identify a difference in
inpatient mortality [marginal effect (ME), -0.56; 95% CI, -1.03 to 0.02], length
of stay (LOS) (ME, 1.72; 95% CI, -3.39 to 6.84), or the rate of 30-day
readmissions (ME, -0.30; 95% CI, -0.82 to 0.22) between the two treatment
techniques for patients with SAH. Clipping was associated with a higher rate of
discharge to rehabilitation (ME, 0.63; 95% CI, 0.24 to 1.01). In sensitivity
analysis, mixed effect regression, and propensity score adjusted regression
models demonstrated identical results. CONCLUSIONS: Using a comprehensive
all-payer cohort of patients in New York State presenting with aneurysmal SAH we
did not identify an association of treatment method with mortality, LOS or 30-day
readmission. Clipping was associated with a higher rate of discharge to
rehabilitation.