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The effect of body mass index at the time of donation on postoperative and remote
consequences of nephrectomy in 189 living-related kidney donors
#MMPMID26413352
Kerkeni W
; Rebai MH
; Bouzouita A
; Chakroun M
; Slama RB
; Abdallah TB
; Derouiche A
; Chebil M
Arab J Urol
2015[Sep]; 13
(3
): 221-4
PMID26413352
show ga
OBJECTIVE: To analyse the effects of baseline body mass index (BMI) on the
postoperative and remote consequences of nephrectomy in living kidney donors, as
body weight is conventionally used as an exclusion criterion for kidney donation
and a BMI of <35 kg/m(2) is often required. PATIENTS AND METHODS: We
retrospectively studied 189 living-related kidney donors who had their
nephrectomy between 1986 and 2009 in our urology department. We recorded the BMI
at the time of donation, and analysed variables after surgery, and
clinico-biological factors remotely. The effect of the initial BMI after surgery
and much later after nephrectomy was assessed. RESULTS: The mean follow-up was
9.28 years. The mean (range) BMI at the time of donation was 26.5
(18.5-41.1) kg/m(2); 33% of donors were overweight (BMI 25-30) and 21% were obese
(?30), with 10.5% having a BMI of >35 kg/m(2). The duration of hospitalisation
was not related to the BMI. There was no significant difference between the mean
BMI of donors with a simple postoperative history and donors who had
complications after surgery. Among obese donors, only 7.7% had a complication,
which was a surgical-site infection in all cases. The baseline BMI was higher
among donors who maintained normal renal function and no proteinuria than in
donors with impaired renal function and/or proteinuria; the difference was not
significant. The occurrence of hypertension or diabetes was independent of
baseline BMI. Donors with dyslipidaemia had no significantly greater baseline BMI
than those with no dyslipidaemia. CONCLUSION: The BMI at the time of kidney
donation does not seem to influence the short- or long-term consequences of
nephrectomy in living donors.