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2015 ; 8
(4
): 258-64
Nephropedia Template TP
gab.com Text
Twit Text FOAVip
Twit Text #
English Wikipedia
Percutaneous Transthoracic Lung Biopsy: Comparison Between C-Arm Cone-Beam CT and
Conventional CT Guidance
#MMPMID26310371
Cheng YC
; Tsai SH
; Cheng Y
; Chen JH
; Chai JW
; Chen CC
Transl Oncol
2015[Aug]; 8
(4
): 258-64
PMID26310371
show ga
BACKGROUND: C-arm cone-beam computed tomography (CBCT) is a comparatively novel
modality for guiding percutaneous transthoracic lung biopsies (PTLBs), and
despite its potential advantages over conventional computed tomography (CCT), a
head-to-head comparison of the two techniques has yet to be reported in the
literature. This study aims to evaluate the diagnostic value and safety of
CBCT-guided PTLB compared to CCT-guided biopsy, with cases performed in a single
hospital. METHODS: A total of 104 PTLB patients were retrospectively analyzed in
this study. 35 PTLBs were performed under CBCT guidance, and 69 PTLBs were
performed under CCT guidance. Diagnostic accuracy, sensitivity, and specificity
for malignancy as well as procedure time, radiation dose of patients, and
complication rate in the two groups were compared. RESULTS: Total procedure time
was significantly lower in the CBCT group (32 ± 11 minutes) compared to the CCT
group (38 ± 9.7 minutes; P = .009), especially among patients ?70 years of age
(CBCT: 33 ± 12 minutes, CCT: 42 ± 13, P = .022). For lesions in the lower lobes,
the CBCT-guided group received significantly reduced effective radiation dose
(2.9 ± 1.6 mSv) than CCT-guided patients (3.7 ± 0.80; P = .042). Diagnostic
accuracy, sensitivity, and specificity for malignancy were comparable between the
two groups, as were post-biopsy complication rates. CONCLUSION: CBCT guidance
significantly reduces the procedure time and radiation exposure for PTLBs
compared with CCT, and should be considered in clinical settings that may be
difficult or time-consuming to perform under CCT.