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10.1016/j.semcdb.2015.06.003

http://scihub22266oqcxt.onion/10.1016/j.semcdb.2015.06.003
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suck abstract from ncbi


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pmid26123688
      Semin+Cell+Dev+Biol 2015 ; 42 (ä): 118-33
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  • Temporally coordinated signals progressively pattern the anteroposterior and dorsoventral body axes #MMPMID26123688
  • Tuazon FB ; Mullins MC
  • Semin Cell Dev Biol 2015[Jun]; 42 (ä): 118-33 PMID26123688 show ga
  • The vertebrate body plan is established through the precise spatiotemporal coordination of morphogen signaling pathways that pattern the anteroposterior (AP) and dorsoventral (DV) axes. Patterning along the AP axis is directed by posteriorizing signals Wnt, fibroblast growth factor (FGF), Nodal, and retinoic acid (RA), while patterning along the DV axis is directed by bone morphogenetic proteins (BMP) ventralizing signals. This review addresses the current understanding of how Wnt, FGF, RA and BMP pattern distinct AP and DV cell fates during early development and how their signaling mechanisms are coordinated to concomitantly pattern AP and DV tissues.
  • |*Body Patterning [MESH]
  • |*Signal Transduction [MESH]
  • |Animals [MESH]
  • |Vertebrates/*embryology/metabolism [MESH]
  • |Xenopus/embryology/metabolism [MESH]


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