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10.1111/dom.12520 http://scihub22266oqcxt.onion/10.1111/dom.12520 C4562072!4562072!26332966     free     free     free Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Diabetes+Obes+Metab 2015 ; 17 (0 1): 33-8 Nephropedia Template TP {{tp|p=26332966|t=2015. Transcriptional control of circadian metabolic rhythms in the liver |pdf=|usr=}}{{26332966}} gab.com Text Transcriptional control of circadian metabolic rhythms in the liver JO: Diabetes Obes Metab http://www.kidney.de/pget.php?&tw=1&pmid=26332966 #FOAvip Diurnal metabolic rhythms add an important temporal dimension to metabolic homeostasis in mammals. While it remains a challenge to untangle the intricate networks of crosstalk among the body clock, nutrient signaling, and tissue metabolism, there is little doubt that the rhythmic nature of nutrient and energy metabolism is a central aspect of metabolic physiology. Disruption of the synchrony between clock and metabolism has been causally linked to diverse pathophysiological states. As such, restoring the rhythmicity of body physiology and therapeutic targeting directed at specific time windows during the day may have important implications in human health and medicine. In this review, we summarize recent findings on the integration of hepatic glucose metabolism and the body clock through a regulatory network centered on the PGC-1 transcriptional coactivators. In addition, we discuss the transcriptional mechanisms underlying circadian control of the autophagy gene program and autophagy in the liver. Twit Text FOAVip Transcriptional control of circadian metabolic rhythms in the liver ????Diabetes Obes Metab http://www.kidney.de/pget.php?&tw=1&pmid=26332966 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=26332966 #FOAvip English Wikipedia <ref>{{Cite pmid|26332966}}</ref> Transcriptional control of circadian metabolic rhythms in the liver #MMPMID26332966 Li S; Lin JD Diabetes Obes Metab 2015[Sep]; 17 (0 1): 33-8 PMID26332966show ga Diurnal metabolic rhythms add an important temporal dimension to metabolic homeostasis in mammals. While it remains a challenge to untangle the intricate networks of crosstalk among the body clock, nutrient signaling, and tissue metabolism, there is little doubt that the rhythmic nature of nutrient and energy metabolism is a central aspect of metabolic physiology. Disruption of the synchrony between clock and metabolism has been causally linked to diverse pathophysiological states. As such, restoring the rhythmicity of body physiology and therapeutic targeting directed at specific time windows during the day may have important implications in human health and medicine. In this review, we summarize recent findings on the integration of hepatic glucose metabolism and the body clock through a regulatory network centered on the PGC-1 transcriptional coactivators. In addition, we discuss the transcriptional mechanisms underlying circadian control of the autophagy gene program and autophagy in the liver. äTranscriptional control of circadian metabolic rhythms in the liver (epmc).pdf DeepDyve Pubget Overpricing