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10.1038/jes.2015.9

http://scihub22266oqcxt.onion/10.1038/jes.2015.9
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C4560677!4560677!25736162
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suck abstract from ncbi


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pmid25736162      J+Expo+Sci+Environ+Epidemiol 2015 ; 25 (6): 593-8
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  • Dust-metal Loadings and the Risk of Childhood Acute Lymphoblastic Leukemia #MMPMID25736162
  • Whitehead TP; Ward MH; Colt JS; Dahl G; Ducore J; Reinier K; Gunier RB; Hammond SK; Rappaport SM; Metayer C
  • J Expo Sci Environ Epidemiol 2015[Nov]; 25 (6): 593-8 PMID25736162show ga
  • We evaluated the relationship between the risk of childhood acute lymphoblastic leukemia (ALL) and levels of metals in carpet dust. A dust sample was collected from the homes of 142 ALL cases and 187 controls participating in the California Childhood Leukemia Study using a high volume small surface sampler (2001?2006). Samples were analyzed using microwave-assisted acid digestion in combination with inductively-coupled plasma mass spectrometry for arsenic, cadmium, chromium, copper, lead, nickel, tin, tungsten, and zinc. Eight metals were detected in at least 85% of the case and control homes; tungsten was detected in less than 15% of homes. Relationships between dust-metal loadings (?g metal per m2 carpet) and ALL risk were modeled using multivariable logistic regression, adjusting for the child?s age, sex, and race/ethnicity and confounders, including household annual income. A doubling of dust-metal loadings was not associated with significant changes in ALL risk [odds ratio (95% confidence interval): arsenic: 0.94 (0.83, 1.05), cadmium: 0.91 (0.80, 1.04), chromium: 0.99 (0.87, 1.12), copper: 0.96 (0.90, 1.03), lead: 1.01 (0.93, 1.10), nickel: 0.92 (0.80, 1.07), tin: 0.93 (0.82, 1.05), and zinc: 0.91 (0.81, 1.02)]. Our findings do not support the hypothesis that metals in carpet dust are risk factors for childhood ALL.
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