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2015 ; 15
(ä): 858
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Meta-analysis of studies on chemical, physical and biological agents in the
control of Aedes aegypti
#MMPMID26341708
Lima EP
; Goulart MO
; Rolim Neto ML
BMC Public Health
2015[Sep]; 15
(ä): 858
PMID26341708
show ga
BACKGROUND: Aedes aegypti is a vector of international concern because it can
transmit to humans three important arboviral diseases: yellow fever, dengue and
chikungunya. Epidemics that are repeated year after year in a variety of urban
centers indicate that there are control failures, allowing the vector to continue
expanding. METHODS: To identify the most effective vector control strategies and
the factors that contributed to the success or failure of each strategy, we
carried out a systematic review with meta-analysis of articles published in 12
databases, from 1974 to the month of December 2013. We evaluated the association
between the use of whatever chemical substance, mechanical agent, biological or
integrated actions against A. aegypti and the control of the vector, as measured
by 10 indicators. RESULTS: We found 2,791 articles, but after careful selection,
only 26 studies remained for analysis related to control interventions
implemented in 15 countries, with 5 biological, 5 chemical, 3 mechanical and 13
integrated strategies. The comparison among all of them, indicated that the
control of A. aegypti is significantly associated with the type of strategy used,
and that integrated interventions consist of the most effective method for
controlling A. aegypti. CONCLUSIONS: The most effective control method was the
integrated approach, considering the influence of eco-bio-social determinants in
the virus-vector-man epidemiological chain, and community involvement, starting
with community empowerment as active agents of vector control.