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Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 J+Lab+Physicians 2015 ; 7 (2): 128-30 Nephropedia Template TP
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Transfusion-acquired Hemoglobinopathies: A Report of Two Cases #MMPMID26417166
Somasundaram V; Purohit A; Manivannan P; Saxena R
J Lab Physicians 2015[Jul]; 7 (2): 128-30 PMID26417166show ga
Transfusion-acquired hemoglobinopathy occurs when a carrier of hemoglobinopathy with no significant abnormalities donates blood, and the blood is transfused to a recipient. This process can lead to spurious results in the recipient without any clinical abnormality or infrequently can result in disastrous situations. The incidental finding of such posttransfusion related abnormal peaks in hemoglobin high-performance liquid chromatography (Hb HPLC) may cause diagnostic dilemmas and result in unnecessary laboratory testing. Here, we report two such cases of transfusion-acquired hemoglobinopathies, which were subsequently resolved by the abnormally low percentage of the Hb variants, transient nature of the peaks, and parental Hb HPLC.