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2015 ; 13
(4
): 271-9
Nephropedia Template TP
gab.com Text
Twit Text FOAVip
Twit Text #
English Wikipedia
Providing Contemporary Access to Historical Biospecimen Collections: Development
of the NHLBI Biologic Specimen and Data Repository Information Coordinating
Center (BioLINCC)
#MMPMID26186276
Giffen CA
; Carroll LE
; Adams JT
; Brennan SP
; Coady SA
; Wagner EL
Biopreserv Biobank
2015[Aug]; 13
(4
): 271-9
PMID26186276
show ga
The National Heart, Lung, and Blood Institute (NHLBI), within the United States'
National Institutes of Health (NIH), established a Biorepository in 1976 that
initially archived biospecimens from population-based blood product safety
surveys. It was later expanded to biospecimens from clinical and epidemiological
studies in heart, lung, and blood disorders. The NHLBI also established a Data
Repository in 2000 to store and distribute study data from NHLBI-sponsored
research. The NHLBI Biologic Specimen and Data Repository Information
Coordinating Center (BioLINCC) was established in 2008 to develop the
infrastructure needed to link the contents of these two related NHLBI
Repositories, facilitate access to repository resources, and streamline request
processes. Three key program subcomponents were developed simultaneously: 1) the
linkage of biospecimen electronic inventory records with their clinical or
characterization data; 2) the development and implementation of a website with
both public-facing information and private processing workspaces; and 3) the
development of processes to maximize efficiency via a web-based system while
maintaining workflow control, document tracking, and secure processes. The
BioLINCC website was launched on October 1, 2009 with eight biospecimen
collections and data from 72 research studies. By the end of the fourth online
year, 38 biospecimen collections were linked and posted, and data from 108
research studies had been made available for request. The number of registered
users by the end of the fourth online year approached 2600, and continues to show
a trend towards an increasing rate of new users per year. BioLINCC has fulfilled
381 requests comprising 851 data collections, as well as 600 teaching dataset
requests and 75 data renewal agreements. 154 biospecimen requests comprising
147,388 biospecimens were fulfilled or actively in process. We conclude that the
BioLINCC program has been successful in its goal to increase the visibility and
utilization of NHLBI biospecimen and data repository resources.
|*Biological Specimen Banks
[MESH]
|Biological Products
[MESH]
|Data Collection
[MESH]
|Humans
[MESH]
|Internet
[MESH]
|National Heart, Lung, and Blood Institute (U.S.)
[MESH]