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2015 ; 2015
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English Wikipedia
Carbohydrate Structure Database: tools for statistical analysis of bacterial,
plant and fungal glycomes
#MMPMID26337239
Egorova KS
; Kondakova AN
; Toukach PV
Database (Oxford)
2015[]; 2015
(ä): ä PMID26337239
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Carbohydrates are biological blocks participating in diverse and crucial
processes both at cellular and organism levels. They protect individual cells,
establish intracellular interactions, take part in the immune reaction and
participate in many other processes. Glycosylation is considered as one of the
most important modifications of proteins and other biologically active molecules.
Still, the data on the enzymatic machinery involved in the carbohydrate synthesis
and processing are scattered, and the advance on its study is hindered by the
vast bulk of accumulated genetic information not supported by any experimental
evidences for functions of proteins that are encoded by these genes. In this
article, we present novel instruments for statistical analysis of glycomes in
taxa. These tools may be helpful for investigating carbohydrate-related enzymatic
activities in various groups of organisms and for comparison of their
carbohydrate content. The instruments are developed on the Carbohydrate Structure
Database (CSDB) platform and are available freely on the CSDB web-site at
http://csdb.glycoscience.ru. Database URL: http://csdb.glycoscience.ru.