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10.1038/srep12769 http://scihub22266oqcxt.onion/10.1038/srep12769 C4558610!4558610 !26335204     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=26335204 &cmd=llinks): Failed to open stream: HTTP request failed! 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Expression of decoy receptor 3 in kidneys is associated with allograft survival after kidney transplant rejection |pdf=|usr=}}{{26335204 }} gab.com Text Expression of decoy receptor 3 in kidneys is associated with allograft survival after kidney transplant rejection JO: Sci Rep http://www.kidney.de/pget.php?&tw=1&pmid=26335204 #FOAvip Decoy receptor 3 (DcR3) expression in kidneys has been shown to predict progression of chronic kidney disease. We prospectively investigated a cohort comprising 96 renal transplant recipients (RTRs) undergoing graft kidney biopsies. Computer-assisted quantitative immunohistochemical staining value of DcR3 in renal tubular epithelial cells (RTECs) was used to determine the predictive role of DcR3 in kidney disease progression. The primary end point was doubling of serum creatinine and/or graft failure. A multivariate Cox proportional hazards model was used to assess the risk of DcR3 expression in rejected kidney grafts toward the renal end point. In total, RTRs with kidney allograft rejection were evaluated and the median follow-up was 30.9 months. The greater expression of DcR3 immunoreactivity in RTECs was correlated with a higher rate of the histopathological concordance of acute T cell-mediated rejection. Compared with 65 non-progressors, 31 progressors had higher DcR3 expression (HDE) regardless of the traditional risk factors. Cox regression analysis showed HDE was significantly associated with the risk of renal end point with a hazard ratio of 3.19 (95% confidence interval, 1.40 to 7.27; P?=?0.006) after adjusting for other variables. In repetitive biopsies, HDE in tissue showed rapid kidney disease progression due to persistent inflammation. Twit Text FOAVip Expression of decoy receptor 3 in kidneys is associated with allograft survival after kidney transplant rejection ????Sci Rep http://www.kidney.de/pget.php?&tw=1&pmid=26335204 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=26335204 #FOAvip English Wikipedia <ref>{{Cite pmid|26335204 }}</ref> Expression of decoy receptor 3 in kidneys is associated with allograft survival after kidney transplant rejection #MMPMID26335204 Weng SC ; Shu KH ; Wu MJ ; Wen MC ; Hsieh SL ; Chen NJ ; Tarng DC Sci Rep 2015[Sep]; 5 (ä): 12769 PMID26335204 show ga Decoy receptor 3 (DcR3) expression in kidneys has been shown to predict progression of chronic kidney disease. We prospectively investigated a cohort comprising 96 renal transplant recipients (RTRs) undergoing graft kidney biopsies. Computer-assisted quantitative immunohistochemical staining value of DcR3 in renal tubular epithelial cells (RTECs) was used to determine the predictive role of DcR3 in kidney disease progression. The primary end point was doubling of serum creatinine and/or graft failure. A multivariate Cox proportional hazards model was used to assess the risk of DcR3 expression in rejected kidney grafts toward the renal end point. In total, RTRs with kidney allograft rejection were evaluated and the median follow-up was 30.9 months. The greater expression of DcR3 immunoreactivity in RTECs was correlated with a higher rate of the histopathological concordance of acute T cell-mediated rejection. Compared with 65 non-progressors, 31 progressors had higher DcR3 expression (HDE) regardless of the traditional risk factors. Cox regression analysis showed HDE was significantly associated with the risk of renal end point with a hazard ratio of 3.19 (95% confidence interval, 1.40 to 7.27; P?=?0.006) after adjusting for other variables. In repetitive biopsies, HDE in tissue showed rapid kidney disease progression due to persistent inflammation. |Biomarkers/metabolism [MESH] |Comorbidity [MESH] |Female [MESH] |Graft Rejection/*metabolism/*mortality [MESH] |Graft Survival [MESH] |Humans [MESH] |Kidney Failure, Chronic/*metabolism/*mortality/*therapy [MESH] |Kidney Transplantation [MESH] |Kidney/metabolism [MESH] |Male [MESH] |Middle Aged [MESH] |Prevalence [MESH] |Receptors, Tumor Necrosis Factor, Member 6b/*metabolism [MESH] |Reproducibility of Results [MESH] |Risk Factors [MESH] |Sensitivity and Specificity [MESH] |Survival Rate [MESH]Expression of decoy receptor 3 in kidneys is associated with allograft(epmc).pdf DeepDyve Pubget Overpricing