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10.1371/journal.pone.0134988

http://scihub22266oqcxt.onion/10.1371/journal.pone.0134988
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C4557972!4557972!26332127
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suck abstract from ncbi


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pmid26332127      PLoS+One 2015 ; 10 (9): ä
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  • What are the Evolutionary Origins of Mitochondria? A Complex Network Approach #MMPMID26332127
  • Carvalho DS; Andrade RFS; Pinho STR; Góes-Neto A; Lobăo TCP; Bomfim GC; El-Hani CN
  • PLoS One 2015[]; 10 (9): ä PMID26332127show ga
  • Mitochondria originated endosymbiotically from an Alphaproteobacteria-like ancestor. However, it is still uncertain which extant group of Alphaproteobacteria is phylogenetically closer to the mitochondrial ancestor. The proposed groups comprise the order Rickettsiales, the family Rhodospirillaceae, and the genus Rickettsia. In this study, we apply a new complex network approach to investigate the evolutionary origins of mitochondria, analyzing protein sequences modules in a critical network obtained through a critical similarity threshold between the studied sequences. The dataset included three ATP synthase subunits (4, 6, and 9) and its alphaproteobacterial homologs (b, a, and c). In all the subunits, the results gave no support to the hypothesis that Rickettsiales are closely related to the mitochondrial ancestor. Our findings support the hypothesis that mitochondria share a common ancestor with a clade containing all Alphaproteobacteria orders, except Rickettsiales.
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