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.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117 J+Extra+Corpor+Technol
2012 ; 44
(3
): 134-8
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gab.com Text
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Our experience with two cardioplegic solutions: dextrose versus non-dextrose in
adult cardiac surgery
#MMPMID23198393
Lessen R
; DiCapua J
; Pekmezaris R
; Walia R
; Bocchieri K
; Jahn L
; Akerman M
; Lesser ML
; Hartman A
J Extra Corpor Technol
2012[Sep]; 44
(3
): 134-8
PMID23198393
show ga
Intraoperative hyperglycemia has been observed to be associated with increased
morbidity and mortality after cardiac surgery. Dextrose cardioplegia is used for
its cardioprotective effects but may lead to intraoperative hyperglycemia and
more postoperative complications. This was a retrospective observational study.
Patient records (n = 2301) were accessed from a large database at a tertiary care
facility. The two groups (dextrose vs. nondextrose) were then matched using
preoperative variables of age, sex, body mass index, wound exposure time,
preoperative HbA1c levels, renal failure, hypertension, and prior cerebrovascular
disease. The following outcomes were recorded: 30-day mortality, sternal wound
infection, stroke, and highest glucose level on cardiopulmonary bypass. The
dextrose cardioplegia group showed statistically higher intraoperative glucose
levels (272.76 +/- 55.92 vs. 182.79 +/- 45, p value = .0001). There was no
difference in postoperative mortality, sternal wound infections or stroke
incidence, nor in other secondary outcomes. The type of cardioplegia solution was
shown to affect glucose levels; however, there was no effect on postoperative
complication rates.