Use of del Nido Cardioplegia for Adult Cardiac Surgery at the Cleveland Clinic:
Perfusion Implications
#MMPMID26357803
Kim K
; Ball C
; Grady P
; Mick S
J Extra Corpor Technol
2014[Dec]; 46
(4
): 317-23
PMID26357803
show ga
Cardiac arrest by cardioplegia provides a reproducible and safe method to induce
and maintain electromechanical cardiac quiescence. Techniques of intraoperative
myocardial protection are constantly evolving. For the past three decades,
modified Buckberg cardioplegia solution has been used for adult cardiac surgery
at the Cleveland Clinic. This formulation serves as the crystalloid component,
which is delivered 4:1 with oxygenated patient's blood to crystalloid. Meanwhile,
our use of the del Nido cardioplegia solution in adult patients, heretofore
primarily used in pediatric cardiac surgical centers, has been increasing over
the past several years. Single-dose, cold blood del Nido cardioplegia can be
delivered antegrade if the duration of the operation will be limited and if there
is no significant coronary artery disease or aortic insufficiency that would
limit the distribution of cardioplegia. The addition of del Nido cardioplegia to
our cardioplegia armamentarium allows us to customize our myocardial protection
strategies for different surgical needs. This article aims to provide information
on technical aspects of del Nido cardioplegia in adult cardiac surgery and its
use at the Cleveland Clinic in the adult surgical population.