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10.1152/physiol.00022.2015

http://scihub22266oqcxt.onion/10.1152/physiol.00022.2015
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C4556828!4556828!26328879
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suck abstract from ncbi

pmid26328879      Physiology+(Bethesda) 2015 ; 30 (5): 340-8
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  • Oxygen Sensing and Homeostasis #MMPMID26328879
  • Prabhakar NR; Semenza GL
  • Physiology (Bethesda) 2015[Sep]; 30 (5): 340-8 PMID26328879show ga
  • The discovery of carotid bodies as sensory receptors for detecting arterial blood oxygen levels, and the identification and elucidation of the roles of hypoxia-inducible factors (HIFs) in oxygen homeostasis have propelled the field of oxygen biology. This review highlights the gas-messenger signaling mechanisms associated with oxygen sensing, as well as transcriptional and non-transcriptional mechanisms underlying the maintenance of oxygen homeostasis by HIFs and their relevance to physiology and pathology.
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