Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\26339332
.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117 Int+J+Clin+Exp+Pathol
2015 ; 8
(7
): 7654-60
Nephropedia Template TP
gab.com Text
Twit Text FOAVip
Twit Text #
English Wikipedia
Corticosteroid therapy for severe acute pancreatitis: a meta-analysis of
randomized, controlled trials
#MMPMID26339332
Dong LH
; Liu ZM
; Wang SJ
; Zhao SJ
; Zhang D
; Chen Y
; Wang YS
Int J Clin Exp Pathol
2015[]; 8
(7
): 7654-60
PMID26339332
show ga
BACKGROUND: Recent reports about the benefits of corticosteroid therapy in
patients with severe acute pancreatitis (SAP) have shown conflicting results. We
aimed to explore the effects of corticosteroid therapy in SAP patients on patient
outcomes by performing a meta-analysis. METHODS: Databases (Medline, EMBASE, Web
of Science, PubMed, Cochrane Library, Chinese Biomedicine Database, and China
Academic Journal Full-Text Database) were queried for all relevant, randomized,
controlled trials investigating corticosteroid therapy in patients with SAP.
RESULTS: Six randomized, controlled trials including 430 SAP patients were
identified. Corticosteroid therapy for SAP was associated with reductions in the
length of hospital stay, the need for surgical intervention, and the mortality
rate (weighted mean difference [WMD]: -9.47, 95% confidence interval [CI]: -16.91
to -2.04, P = 0.01; odds ratio [OR]: 0.35, 95% CI: 0.18-0.67, P = 0.002; OR:
0.45, 95% CI: 0.22-0.94, P = 0.03). There were no significant differences in the
complication rates or Physiology and Chronic Health Evaluation II (APACHE II)
scores in patients with or without corticosteroid therapy. CONCLUSION:
Corticosteroid therapy may improve outcomes in patients with SAP.