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10.3389/fcell.2015.00053 http://scihub22266oqcxt.onion/10.3389/fcell.2015.00053 C4555086!4555086!26389118     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Front+Cell+Dev+Biol 2015 ; 3 (ä): ä Nephropedia Template TP {{tp|p=26389118|t=2015. Developing a functional urinary bladder: a neuronal context |pdf=|usr=}}{{26389118}} gab.com Text Developing a functional urinary bladder: a neuronal context JO: Front Cell Dev Biol http://www.kidney.de/pget.php?&tw=1&pmid=26389118 #FOAvip The development of organs occurs in parallel with the formation of their nerve supply. The innervation of pelvic organs (lower urinary tract, hindgut, and sexual organs) is complex and we know remarkably little about the mechanisms that form these neural pathways. The goal of this short review is to use the urinary bladder as an example to stimulate interest in this question. The bladder requires a healthy mature nervous system to store urine and release it at behaviorally appropriate times. Understanding the mechanisms underlying the construction of these neural circuits is not only relevant to defining the basis of developmental problems but may also suggest strategies to restore connectivity and function following injury or disease in adults. The bladder nerve supply comprises multiple classes of sensory, and parasympathetic or sympathetic autonomic effector (motor) neurons. First, we define the developmental endpoint by describing this circuitry in adult rodents. Next we discuss the innervation of the developing bladder, identifying challenges posed by this area of research. Last we provide examples of genetically modified mice with bladder dysfunction and suggest potential neural contributors to this state. Twit Text FOAVip Developing a functional urinary bladder: a neuronal context ????Front Cell Dev Biol http://www.kidney.de/pget.php?&tw=1&pmid=26389118 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=26389118 #FOAvip English Wikipedia <ref>{{Cite pmid|26389118}}</ref> Developing a functional urinary bladder: a neuronal context #MMPMID26389118 Keast JR; Smith-Anttila CJA; Osborne PB Front Cell Dev Biol 2015[]; 3 (ä): ä PMID26389118show ga The development of organs occurs in parallel with the formation of their nerve supply. The innervation of pelvic organs (lower urinary tract, hindgut, and sexual organs) is complex and we know remarkably little about the mechanisms that form these neural pathways. The goal of this short review is to use the urinary bladder as an example to stimulate interest in this question. The bladder requires a healthy mature nervous system to store urine and release it at behaviorally appropriate times. Understanding the mechanisms underlying the construction of these neural circuits is not only relevant to defining the basis of developmental problems but may also suggest strategies to restore connectivity and function following injury or disease in adults. The bladder nerve supply comprises multiple classes of sensory, and parasympathetic or sympathetic autonomic effector (motor) neurons. First, we define the developmental endpoint by describing this circuitry in adult rodents. Next we discuss the innervation of the developing bladder, identifying challenges posed by this area of research. Last we provide examples of genetically modified mice with bladder dysfunction and suggest potential neural contributors to this state. äDeveloping a functional urinary bladder: a neuronal context (epmc).pdf DeepDyve Pubget Overpricing