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10.1016/j.tcb.2015.05.003 http://scihub22266oqcxt.onion/10.1016/j.tcb.2015.05.003 C4554970!4554970!26045257     free     free     free       Trends+Cell+Biol 2015 ; 25 (9): 514-22 Nephropedia Template TP {{tp|p=26045257|t=2015. R-Loops Breaking Bad |pdf=|usr=}}{{26045257}} gab.com Text R-Loops Breaking Bad JO: Trends Cell Biol http://www.kidney.de/pget.php?&tw=1&pmid=26045257 #FOAvip R-loops, nucleic acid structures consisting of an RNA-DNA hybrid and displaced single-stranded DNA, are ubiquitous in organisms from bacteria to mammals. First described in bacteria where they initiate DNA replication, it now appears that R-loops regulate diverse cellular processes such as gene expression, immunoglobulin class switching and DNA repair. Changes in R-loop regulation induce DNA damage and genome instability, and recently it was shown that R-loops are associated with neurodegenerative disorders. Here, we discuss recent developments in the field; in particular, the regulation and effects of R-loops in cells, their effect on genomic and epigenomic stability and their potential contribution to the origin of certain diseases, including cancer and neurodegenerative disorders. Twit Text FOAVip R-Loops Breaking Bad ????Trends Cell Biol http://www.kidney.de/pget.php?&tw=1&pmid=26045257 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=26045257 #FOAvip English Wikipedia <ref>{{Cite pmid|26045257}}</ref> R-Loops Breaking Bad #MMPMID26045257 Sollier J; Cimprich KA Trends Cell Biol 2015[Sep]; 25 (9): 514-22 PMID26045257show ga R-loops, nucleic acid structures consisting of an RNA-DNA hybrid and displaced single-stranded DNA, are ubiquitous in organisms from bacteria to mammals. First described in bacteria where they initiate DNA replication, it now appears that R-loops regulate diverse cellular processes such as gene expression, immunoglobulin class switching and DNA repair. Changes in R-loop regulation induce DNA damage and genome instability, and recently it was shown that R-loops are associated with neurodegenerative disorders. Here, we discuss recent developments in the field; in particular, the regulation and effects of R-loops in cells, their effect on genomic and epigenomic stability and their potential contribution to the origin of certain diseases, including cancer and neurodegenerative disorders. äR-Loops Breaking Bad (epmc).pdf DeepDyve Pubget Overpricing