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10.1097/MD.0000000000000591 http://scihub22266oqcxt.onion/10.1097/MD.0000000000000591 C4553957!4553957!25738482     free     free     free Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 265.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Medicine+(Baltimore) 2015 ; 94 (9): ä Nephropedia Template TP {{tp|p=25738482|t=2015. Clinical and Pathological Findings of a Fatal Systemic Capillary Leak Syndrome (Clarkson Disease): A Case Report |pdf=|usr=}}{{25738482}} gab.com Text Clinical and Pathological Findings of a Fatal Systemic Capillary Leak Syndrome (Clarkson Disease): A Case Report JO: Medicine (Baltimore) http://www.kidney.de/pget.php?&tw=1&pmid=25738482 #FOAvip Systemic capillary leak syndrome (SCLS) is a rare disorder with episodes of hypotension, hypoalbuminemia, and hemoconcentration. During attacks endothelial hyperpermeability results in leakage of plasma proteins into the interstitial space. Attacks vary in severity and may be lethal.A 49-year-old previously healthy man was admitted to hospital for hypovolemic shock, anasarca with pleuropericardial effusion, muscle fatigue, and oliguria occurring after a flu-like syndrome. Laboratory data showed an increase in hematocrit (65%), leucocytes (24.590??/L), creatinine (2.5?mg/dL), creatine phosphokinase (10.000?U/L), and a decrease in serum albumin (17?g/L) without proteinuria. Immunoglobulins of class G/? monoclonal gammopathy were detected (1.3?g/L). The initial suspicions addressed to a protein-loosing syndrome or to an effort-related rhabdomyolysis. Initial therapy was based on steroids, albumin, and high molecular weight plasma expanders (hydroxyethyl starch). Because of high hematocrit, phlebotomy was also performed. The patient had complete clinical remission and a diagnosis of SCLS was finally made. He received prophylactic therapy with verapamil and theophylline that was self-stopped for intolerance (hypotension and tachycardia). He had a new crisis 2 days after a physical effort, and was admitted in intensive care unit. The patient died for severe hypovolemic shock with multiorgan failure and sudden cardiac arrest 15 hours after hospital admission. Postmortem investigation revealed massive interstitial edema of main organs with myocardial hyperacute ischemia.Studies on SCLS are limited for the rarity of the disease and its unpredictable course. Both prophylactic and acute crisis treatments are empirical and optimal management of severe attacks is still lacking. Twit Text FOAVip Clinical and Pathological Findings of a Fatal Systemic Capillary Leak Syndrome (Clarkson Disease): A Case Report ????Medicine (Baltimore) http://www.kidney.de/pget.php?&tw=1&pmid=25738482 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=25738482 #FOAvip English Wikipedia <ref>{{Cite pmid|25738482}}</ref> Clinical and Pathological Findings of a Fatal Systemic Capillary Leak Syndrome (Clarkson Disease): A Case Report #MMPMID25738482 Zancanaro A; Serafini F; Fantin G; Murer B; Cicardi M; Bonanni L; Dalla Vestra M; Scanferlato M; Mazzanti G; Presotto F Medicine (Baltimore) 2015[Mar]; 94 (9): ä PMID25738482show ga Systemic capillary leak syndrome (SCLS) is a rare disorder with episodes of hypotension, hypoalbuminemia, and hemoconcentration. During attacks endothelial hyperpermeability results in leakage of plasma proteins into the interstitial space. Attacks vary in severity and may be lethal.A 49-year-old previously healthy man was admitted to hospital for hypovolemic shock, anasarca with pleuropericardial effusion, muscle fatigue, and oliguria occurring after a flu-like syndrome. Laboratory data showed an increase in hematocrit (65%), leucocytes (24.590??/L), creatinine (2.5?mg/dL), creatine phosphokinase (10.000?U/L), and a decrease in serum albumin (17?g/L) without proteinuria. Immunoglobulins of class G/? monoclonal gammopathy were detected (1.3?g/L). The initial suspicions addressed to a protein-loosing syndrome or to an effort-related rhabdomyolysis. Initial therapy was based on steroids, albumin, and high molecular weight plasma expanders (hydroxyethyl starch). Because of high hematocrit, phlebotomy was also performed. The patient had complete clinical remission and a diagnosis of SCLS was finally made. He received prophylactic therapy with verapamil and theophylline that was self-stopped for intolerance (hypotension and tachycardia). He had a new crisis 2 days after a physical effort, and was admitted in intensive care unit. The patient died for severe hypovolemic shock with multiorgan failure and sudden cardiac arrest 15 hours after hospital admission. Postmortem investigation revealed massive interstitial edema of main organs with myocardial hyperacute ischemia.Studies on SCLS are limited for the rarity of the disease and its unpredictable course. Both prophylactic and acute crisis treatments are empirical and optimal management of severe attacks is still lacking. äClinical and Pathological Findings of a Fatal Systemic Capillary Leak (epmc).pdf DeepDyve Pubget Overpricing