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10.1007/s11899-015-0270-5 http://scihub22266oqcxt.onion/10.1007/s11899-015-0270-5 C4553153!4553153!26126599     free     free     free Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Curr+Hematol+Malig+Rep 2015 ; 10 (3): 282-91 Nephropedia Template TP {{tp|p=26126599|t=2015. Myelodysplastic Syndromes Diagnosis: What Is the Role of Molecular Testing?|pdf=|usr=}}{{26126599}} gab.com Text Myelodysplastic Syndromes Diagnosis: What Is the Role of Molecular Testing JO: Curr Hematol Malig Rep http://www.kidney.de/pget.php?&tw=1&pmid=26126599 #FOAvip Diagnosing a myelodysplastic syndrome (MDS) can be challenging. Somatic mutations are common in MDS and might have diagnostic utility in patients with idiopathic cytopenias of undetermined significance (ICUS). However, using mutations to diagnose MDS is complicated by several issues: (1) no gene is mutated in most cases, (2) no mutated gene is highly specific for MDS, (3) clonal hematopoiesis is common in older individuals without disease, and (4) we lack outcome data for ICUS patients with clonal cytopenias of undetermined significance (CCUS). Despite these caveats, genetic sequencing can inform the diagnosis of MDS. CCUS patients more closely resemble patients with MDS than age matched controls with somatic mutations. Genetic testing can identify alternative diagnoses in cytopenic patients and help risk stratify those with proven MDS. While we cannot include somatic mutations in the diagnostic definition of MDS now, testing to recognize CCUS will help characterize outcomes in these diagnostically challenging patients. Twit Text FOAVip Myelodysplastic Syndromes Diagnosis: What Is the Role of Molecular Testing ????Curr Hematol Malig Rep http://www.kidney.de/pget.php?&tw=1&pmid=26126599 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=26126599 #FOAvip English Wikipedia <ref>{{Cite pmid|26126599}}</ref> Myelodysplastic Syndromes Diagnosis: What Is the Role of Molecular Testing? #MMPMID26126599 Bejar R Curr Hematol Malig Rep 2015[]; 10 (3): 282-91 PMID26126599show ga Diagnosing a myelodysplastic syndrome (MDS) can be challenging. Somatic mutations are common in MDS and might have diagnostic utility in patients with idiopathic cytopenias of undetermined significance (ICUS). However, using mutations to diagnose MDS is complicated by several issues: (1) no gene is mutated in most cases, (2) no mutated gene is highly specific for MDS, (3) clonal hematopoiesis is common in older individuals without disease, and (4) we lack outcome data for ICUS patients with clonal cytopenias of undetermined significance (CCUS). Despite these caveats, genetic sequencing can inform the diagnosis of MDS. CCUS patients more closely resemble patients with MDS than age matched controls with somatic mutations. Genetic testing can identify alternative diagnoses in cytopenic patients and help risk stratify those with proven MDS. While we cannot include somatic mutations in the diagnostic definition of MDS now, testing to recognize CCUS will help characterize outcomes in these diagnostically challenging patients. äMyelodysplastic Syndromes Diagnosis: What Is the Role of Molecular Tes(epmc).pdf DeepDyve Pubget Overpricing