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10.1371/journal.pone.0137018 http://scihub22266oqcxt.onion/10.1371/journal.pone.0137018 C4552160!4552160!26313904     free     free     free Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       PLoS+One 2015 ; 10 (8): ä Nephropedia Template TP {{tp|p=26313904|t=2015. Shedding of Infectious Borna Disease Virus-1 in Living Bicolored White-Toothed Shrews |pdf=|usr=}}{{26313904}} gab.com Text Shedding of Infectious Borna Disease Virus-1 in Living Bicolored White-Toothed Shrews JO: PLoS One http://www.kidney.de/pget.php?&tw=1&pmid=26313904 #FOAvip Background: Many RNA viruses arise from animal reservoirs, namely bats, rodents and insectivores but mechanisms of virus maintenance and transmission still need to be addressed. The bicolored white-toothed shrew (Crocidura leucodon) has recently been identified as reservoir of the neurotropic Borna disease virus 1 (BoDV-1). Principal Findings: Six out of eleven wild living bicoloured white-toothed shrews were trapped and revealed to be naturally infected with BoDV-1. All shrews were monitored in captivity in a long-term study over a time period up to 600 days that differed between the individual shrews. Interestingly, all six animals showed an asymptomatic course of infection despite virus shedding via various routes indicating a highly adapted host-pathogen interaction. Infectious virus and viral RNA were demonstrated in saliva, urine, skin swabs, lacrimal fluid and faeces, both during the first 8 weeks of the investigation period and for long time shedding after more than 250 days in captivity. Conclusions: The various ways of shedding ensure successful virus maintenance in the reservoir population but also transmission to accidental hosts such as horses and sheep. Naturally BoDV-1-infected living shrews serve as excellent tool to unravel host and pathogen factors responsible for persistent viral co-existence in reservoir species while maintaining their physiological integrity despite high viral load in many organ systems. Twit Text FOAVip Shedding of Infectious Borna Disease Virus-1 in Living Bicolored White-Toothed Shrews ????PLoS One http://www.kidney.de/pget.php?&tw=1&pmid=26313904 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=26313904 #FOAvip English Wikipedia <ref>{{Cite pmid|26313904}}</ref> Shedding of Infectious Borna Disease Virus-1 in Living Bicolored White-Toothed Shrews #MMPMID26313904 Nobach D; Bourg M; Herzog S; Lange-Herbst H; Encarnação JA; Eickmann M; Herden C PLoS One 2015[]; 10 (8): ä PMID26313904show ga Background: Many RNA viruses arise from animal reservoirs, namely bats, rodents and insectivores but mechanisms of virus maintenance and transmission still need to be addressed. The bicolored white-toothed shrew (Crocidura leucodon) has recently been identified as reservoir of the neurotropic Borna disease virus 1 (BoDV-1). Principal Findings: Six out of eleven wild living bicoloured white-toothed shrews were trapped and revealed to be naturally infected with BoDV-1. All shrews were monitored in captivity in a long-term study over a time period up to 600 days that differed between the individual shrews. Interestingly, all six animals showed an asymptomatic course of infection despite virus shedding via various routes indicating a highly adapted host-pathogen interaction. Infectious virus and viral RNA were demonstrated in saliva, urine, skin swabs, lacrimal fluid and faeces, both during the first 8 weeks of the investigation period and for long time shedding after more than 250 days in captivity. Conclusions: The various ways of shedding ensure successful virus maintenance in the reservoir population but also transmission to accidental hosts such as horses and sheep. Naturally BoDV-1-infected living shrews serve as excellent tool to unravel host and pathogen factors responsible for persistent viral co-existence in reservoir species while maintaining their physiological integrity despite high viral load in many organ systems. äShedding of Infectious Borna Disease Virus-1 in Living Bicolored White(epmc).pdf DeepDyve Pubget Overpricing