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2015 ; 31
(2
): 108-13
Nephropedia Template TP
gab.com Text
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Twit Text #
English Wikipedia
Magnetic resonance imaging of the left atrial appendage post pulmonary vein
isolation: Implications for percutaneous left atrial appendage occlusion
#MMPMID26336541
Singh SM
; Jimenez-Juan L
; Danon A
; Bastarrika G
; Shmatukha AV
; Wright GA
; Crystal E
J Arrhythm
2015[Apr]; 31
(2
): 108-13
PMID26336541
show ga
BACKGROUND: There is increasing interest in performing left atrial appendage
(LAA) occlusion at the time of atrial fibrillation (AF) ablation procedures.
However, to date there has been no description of the acute changes to the LAA
immediately following pulmonary vein (PV) isolation and additional left atrium
(LA) substrate modification. This study assessed changes in the size and tissue
characteristics of the LAA ostium in patients undergoing PV isolation. METHODS:
This series included 8 patients who underwent cardiovascular magnetic resonance
evaluation of the LA with delayed enhancement magnetic resonance imaging and
contrast enhanced 3-D magnetic resonance angiography pre-, within 48 h of, and 3
months post ablation. Two independent cardiac radiologists evaluated the ostial
LAA diameters and area at each time point in addition to the presence of
gadolinium enhancement. RESULTS: Compared to pre-ablation values, the respective
median differences in oblique diameters and LAA area were +1.8 mm, +1.7 mm, and
+0.6 cm(2) immediately post ablation (all NS) and -2.7 mm, -2.3 mm, and
-0.5 cm(2) at 3 months (all NS). No delayed enhancement was detected in the LAA
post ablation. CONCLUSION: No significant change to LAA diameter, area, or tissue
characteristics was noted after PV isolation. While these findings suggest the
safety and feasibility of concomitant PV isolation and LAA device occlusion, the
variability in the degree and direction of change of the LAA measurements
highlights the need for further study.