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2015 ; 49
(1
): 37-43
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gab.com Text
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English Wikipedia
Polycyclic Aromatic Hydrocarbon, Haematological and Oxidative Stress Levels in
Commercial Photocopier Operators In Lagos, Nigeria
#MMPMID26339083
Awodele O
; Akindele AJ
; Adebowale GO
; Adeyemi OO
Ghana Med J
2015[Mar]; 49
(1
): 37-43
PMID26339083
show ga
BACKGROUND: Human exposure to hazardous substances in the environment has been
known to play an important role in the pathogenesis of some diseases.
Photocopying machines have become a cheap source of self-employment in Nigeria.
For obvious reasons the highest level of patronage is encountered in the campuses
of educational institutions. However, the persons who operate the machines are
always exposed to possible hazards associated with the job without protective
devices. OBJECTIVE: This study investigated the levels of oxidative stress,
polycyclic aromatic hydrocarbon (PAH) and haematological parameters in blood
samples of photocopier operators. METHODS: The experimental procedure involved 50
consented subjects selected based on some criteria. The haematological
parameters, oxidative stress and PAH levels were determined using standard
methods. RESULTS: The results showed no significant difference (p ? 0.05) in the
haematological parameters between the test subjects and the controls. However,
there were duration on the job (yrs) dependent significant decrease in the level
of superoxide dismutase (SOD) of the photocopier operators compared with the
controls (> 5 years p? 0.0001; 4-5 years p?0.001). The level of reduced
glutathione (GSH) was significantly decreased across all lengths of duration on
the job compared with the controls. CONCLUSION: The findings in this study
revealed increased level of oxidative stress in photocopier operators with no
significant change in haematological parameters. The health implication of
operating photocopiers call for quick health education and intervention tailored
to monitoring and guiding the photocopier operators. This will help to prevent or
manage continuous exposure to the hazards of photocopying machines.