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10.5664/jcsm.5028

http://scihub22266oqcxt.onion/10.5664/jcsm.5028
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suck abstract from ncbi


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pmid25979096      J+Clin+Sleep+Med ä ; 11 (9): 1063-5
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  • Hypocretin Deficiency Associated with Narcolepsy Type 1 and Central Hypoventilation Syndrome in Neurosarcoidosis of the Hypothalamus #MMPMID25979096
  • Mayo MC; Deng JC; Albores J; Zeidler M; Harper RM; Avidan AY
  • J Clin Sleep Med ä[]; 11 (9): 1063-5 PMID25979096show ga
  • We report a case of a 53-year-old man presenting with depressed alertness and severe excessive sleepiness in the setting of neurosarcoidosis. Neuroimaging demonstrated hypothalamic destruction due to sarcoidosis with a CSF hypocretin level of 0 pg/mL. The patient also experienced respiratory depression that presumably resulted from hypocretin-mediated hypothalamic dysfunction as a result of extensive diencephalic injury. This is a novel case, demonstrating both hypocretin deficiency syndrome, as well as respiratory dysfunction from destruction of hypocretin neurons and extensive destruction of key diencephalic structures secondary to the underlying neurosarcoidosis.Citation:: May MC, Deng JC, Albores J, Zeidler M, Harper RM, Avidan AY. Hypocretin deficiency associated with narcolepsy type 1 and central hypoventilation syndrome in neurosarcoidosis of the hypothalamus. J Clin Sleep Med 2015;11(9):1063?1065.
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