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10.1002/dvg.20396 http://scihub22266oqcxt.onion/10.1002/dvg.20396 C4539156!4539156!18543320     free     free     free       Genesis 2008 ; 46 (6): 300-7 Nephropedia Template TP {{tp|p=18543320|t=2008. Cre-Mediated Recombination in Mouse Clara Cells |pdf=|usr=}}{{18543320}} gab.com Text Cre-Mediated Recombination in Mouse Clara Cells JO: Genesis http://www.kidney.de/pget.php?&tw=1&pmid=18543320 #FOAvip Clara cells are nonciliated secretory cells lining the respiratory epithelium and are easily identified by the expression of Clara cell secretory protein (CCSP). To investigate molecular mechanism(s) regulating Clara cell function in the lungs, Cre recombinase was inserted into exon 1 of the CCSP, generating two novel mouse models, CCSPCre-Neo and CCSPCre. These two models differ only by the inclusion of the neomycin resistance gene. These mice were bred to the R26R reporter mouse to investigate the tissue and cell specificity of Cre-mediated recombination. The efficiency of Cre recombination in the CCSPCre mouse model was higher than in the CCSPCre-Neo mouse model. Recombination was detected at D 4.5 in CCSPCre-Neo/R26R mice and at D 0.5 in CCSPCre/R26R mice. The CCSPCre-Neo and CCSPCre mouse models provide valuable tools for the ablation of genes in the post-natal mouse Clara cells. Twit Text FOAVip Cre-Mediated Recombination in Mouse Clara Cells ????Genesis http://www.kidney.de/pget.php?&tw=1&pmid=18543320 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=18543320 #FOAvip English Wikipedia <ref>{{Cite pmid|18543320}}</ref> Cre-Mediated Recombination in Mouse Clara Cells #MMPMID18543320 Li H; Cho SN; Evans CM; Dickey BF; Jeong JW; DeMayo FJ Genesis 2008[Jun]; 46 (6): 300-7 PMID18543320show ga Clara cells are nonciliated secretory cells lining the respiratory epithelium and are easily identified by the expression of Clara cell secretory protein (CCSP). To investigate molecular mechanism(s) regulating Clara cell function in the lungs, Cre recombinase was inserted into exon 1 of the CCSP, generating two novel mouse models, CCSPCre-Neo and CCSPCre. These two models differ only by the inclusion of the neomycin resistance gene. These mice were bred to the R26R reporter mouse to investigate the tissue and cell specificity of Cre-mediated recombination. The efficiency of Cre recombination in the CCSPCre mouse model was higher than in the CCSPCre-Neo mouse model. Recombination was detected at D 4.5 in CCSPCre-Neo/R26R mice and at D 0.5 in CCSPCre/R26R mice. The CCSPCre-Neo and CCSPCre mouse models provide valuable tools for the ablation of genes in the post-natal mouse Clara cells. äCre-Mediated Recombination in Mouse Clara Cells (epmc).pdf DeepDyve Pubget Overpricing