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2014 ; 54
(12
): 1014-21
Nephropedia Template TP
gab.com Text
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Third Ventriculostomy in Late-onset Idiopathic Aqueductal Stenosis Treatment: A
Focus on Clinical Presentation and Radiological Diagnosis
#MMPMID25446383
Locatelli M
; Draghi R
; DI Cristofori A
; Carrabba G
; Zavanone M
; Pluderi M
; Spagnoli D
; Rampini P
Neurol Med Chir (Tokyo)
2014[]; 54
(12
): 1014-21
PMID25446383
show ga
Endoscopic third ventriculostomy (ETV) is considered the gold standard treatment
for obstructive hydrocephalus due to partial or complete obstruction of
cerebrospinal fluid (CSF) ventricular pathways caused by mass lesions. However
long-term efficacy of this procedure remains controversial as treatment of
chronic adult hydrocephalus due to stenosis of Sylvian acqueduct [late-onset
idiopathic aqueductal stenosis (LIAS)]. The authors describe clinical
presentation, diagnostic investigations in patients affected by LIAS, and define
their clinical and radiological outcome after ETV. From January 2003 to December
2008, 13 consecutive LIAS patients treated by ETV were retrospectively reviewed.
Pre- and post-operative clinical and radiological findings, including
conventional and phase-contrast (PC) cine magnetic resonance imaging (MRI) were
investigated. ETV was successfully performed in all patients. Patient's
neurological condition improved. No one required a second ETV procedure or shunt
implantation. Clinical and radiological results reveal a satisfactory outcome of
LIAS patients treated by ETV. At follow-up a clinical improvement could be
demonstrated in all cases. Selection criteria of LIAS patients seem to be crucial
to obtain satisfactory and long-lasting results. Even in elderly patients with
chronic hydrocephalus, ETV can be considered the treatment of choice.
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