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10.1016/j.brainres.2014.11.033 http://scihub22266oqcxt.onion/10.1016/j.brainres.2014.11.033 C4532652!4532652 !25482663     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=25482663 &cmd=llinks): Failed to open stream: HTTP request failed! 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Multiple cellular cascades participate in long-term potentiation and in hippocampus-dependent learning |pdf=|usr=}}{{25482663 }} gab.com Text Multiple cellular cascades participate in long-term potentiation and in hippocampus-dependent learning JO: Brain Res http://www.kidney.de/pget.php?&tw=1&pmid=25482663 #FOAvip Since its discovery by Bliss and Lomo, the phenomenon of long-term potentiation (LTP) has been extensively studied, as it was viewed as a potential cellular mechanism of learning and memory. Over the years, many signaling cascades have been implicated in its induction, consolidation and maintenance, raising questions regarding its real significance. Here, we review several of the most commonly studie signaling cascades and discuss how they converge on a common set of mechanisms likely to be involved in the maintenance of LTP. We further argue that the existence of cross-talks between these different signaling cascades can not only account for several discrepancies in the literature, but also account for the existence of different forms of LTP, which can be engaged by different types of stimulus parameters under different experimental conditions. Finally, we discuss how the understanding of the diversity of LTP mechanisms can help us understand the diversity of the types of learning and memory. This article is part of a Special Issue entitled SI: Brain and Memory. Twit Text FOAVip Multiple cellular cascades participate in long-term potentiation and in hippocampus-dependent learning ????Brain Res http://www.kidney.de/pget.php?&tw=1&pmid=25482663 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=25482663 #FOAvip English Wikipedia <ref>{{Cite pmid|25482663 }}</ref> Multiple cellular cascades participate in long-term potentiation and in hippocampus-dependent learning #MMPMID25482663 Baudry M ; Zhu G ; Liu Y ; Wang Y ; Briz V ; Bi X Brain Res 2015[Sep]; 1621 (ä): 73-81 PMID25482663 show ga Since its discovery by Bliss and Lomo, the phenomenon of long-term potentiation (LTP) has been extensively studied, as it was viewed as a potential cellular mechanism of learning and memory. Over the years, many signaling cascades have been implicated in its induction, consolidation and maintenance, raising questions regarding its real significance. Here, we review several of the most commonly studie signaling cascades and discuss how they converge on a common set of mechanisms likely to be involved in the maintenance of LTP. We further argue that the existence of cross-talks between these different signaling cascades can not only account for several discrepancies in the literature, but also account for the existence of different forms of LTP, which can be engaged by different types of stimulus parameters under different experimental conditions. Finally, we discuss how the understanding of the diversity of LTP mechanisms can help us understand the diversity of the types of learning and memory. This article is part of a Special Issue entitled SI: Brain and Memory. |*Long-Term Potentiation [MESH] |*Signal Transduction [MESH] |Animals [MESH] |Calcium-Calmodulin-Dependent Protein Kinase Type 2/metabolism [MESH] |Calpain/metabolism [MESH] |Cyclic AMP-Dependent Protein Kinases/metabolism [MESH] |Dendritic Spines/metabolism [MESH] |Hippocampus/*metabolism [MESH] |Humans [MESH] |Learning/*physiology [MESH] |MAP Kinase Signaling System [MESH] |Memory/*physiology [MESH] |Neurons/metabolism [MESH]Multiple cellular cascades participate in long-term potentiation and i(epmc).pdf DeepDyve Pubget Overpricing