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Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Philos+Trans+R+Soc+Lond+B+Biol+Sci 2015 ; 370 (1677): ä Nephropedia Template TP
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Illuminating neural circuits and behaviour in Caenorhabditis elegans with optogenetics #MMPMID26240427
Fang-Yen C; Alkema MJ; Samuel ADT
Philos Trans R Soc Lond B Biol Sci 2015[Sep]; 370 (1677): ä PMID26240427show ga
The development of optogenetics, a family of methods for using light to control neural activity via light-sensitive proteins, has provided a powerful new set of tools for neurobiology. These techniques have been particularly fruitful for dissecting neural circuits and behaviour in the compact and transparent roundworm Caenorhabditis elegans. Researchers have used optogenetic reagents to manipulate numerous excitable cell types in the worm, from sensory neurons, to interneurons, to motor neurons and muscles. Here, we show how optogenetics applied to this transparent roundworm has contributed to our understanding of neural circuits.