Use my Search Websuite to scan PubMed, PMCentral, Journal Hosts and Journal Archives, FullText. Kick-your-searchterm to multiple Engines kick-your-query now !>

A dictionary by aggregated review articles of nephrology, medicine and the life sciences Your one-stop-run pathway from word to the immediate pdf of peer-reviewed on-topic knowledge.

10.1242/dmm.018523 http://scihub22266oqcxt.onion/10.1242/dmm.018523 C4527280!4527280!26035382     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=26035382&cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Dis+Model+Mech 2015 ; 8 (8): 903-17 Nephropedia Template TP {{tp|p=26035382|t=2015. Deducing the stage of origin of Wilms tumours from a developmental series of Wt1-mutant mice |pdf=|usr=}}{{26035382}} gab.com Text Deducing the stage of origin of Wilms tumours from a developmental series of Wt1-mutant mice JO: Dis Model Mech http://www.kidney.de/pget.php?&tw=1&pmid=26035382 #FOAvip Wilms' tumours, paediatric kidney cancers, are the archetypal example of tumours caused through the disruption of normal development. The genetically best-defined subgroup of Wilms' tumours is the group caused by biallelic loss of the WT1 tumour suppressor gene. Here, we describe a developmental series of mouse models with conditional loss of Wt1 in different stages of nephron development before and after the mesenchymal-to-epithelial transition (MET). We demonstrate that Wt1 is essential for normal development at all kidney developmental stages under study. Comparison of genome-wide expression data from the mutant mouse models with human tumour material of mutant or wild-type WT1 datasets identified the stage of origin of human WT1-mutant tumours, and emphasizes fundamental differences between the two human tumour groups due to different developmental stages of origin. Twit Text FOAVip Deducing the stage of origin of Wilms tumours from a developmental series of Wt1-mutant mice ????Dis Model Mech http://www.kidney.de/pget.php?&tw=1&pmid=26035382 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=26035382 #FOAvip English Wikipedia <ref>{{Cite pmid|26035382}}</ref> Deducing the stage of origin of Wilms tumours from a developmental series of Wt1-mutant mice #MMPMID26035382 Berry RL; Ozdemir DD; Aronow B; Lindström NO; Dudnakova T; Thornburn A; Perry P; Baldock R; Armit C; Joshi A; Jeanpierre C; Shan J; Vainio S; Baily J; Brownstein D; Davies J; Hastie ND; Hohenstein P Dis Model Mech 2015[Aug]; 8 (8): 903-17 PMID26035382show ga Wilms' tumours, paediatric kidney cancers, are the archetypal example of tumours caused through the disruption of normal development. The genetically best-defined subgroup of Wilms' tumours is the group caused by biallelic loss of the WT1 tumour suppressor gene. Here, we describe a developmental series of mouse models with conditional loss of Wt1 in different stages of nephron development before and after the mesenchymal-to-epithelial transition (MET). We demonstrate that Wt1 is essential for normal development at all kidney developmental stages under study. Comparison of genome-wide expression data from the mutant mouse models with human tumour material of mutant or wild-type WT1 datasets identified the stage of origin of human WT1-mutant tumours, and emphasizes fundamental differences between the two human tumour groups due to different developmental stages of origin. äDeducing the stage of origin of Wilms tumours from a developmental se(epmc).pdf DeepDyve Pubget Overpricing