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2015 ; 3
(3
): 238-42
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Histopathological study using computer database of 10?000 consecutive gastric
specimens: (1) benign conditions
#MMPMID25688102
Terada T
Gastroenterol Rep (Oxf)
2015[Aug]; 3
(3
): 238-42
PMID25688102
show ga
Using a computer database, the author investigated the histopathology of 10 000
consecutive gastric specimens, taken in the last 12 years (2002-2013) at the
pathology laboratory of a Japanese hospital. Re-observation of the already
examined histological sections was done when the histological diagnosis and
findings on the computer data base were not very obvious. The gastric specimens
were identified as 8579 benign conditions and 1421 malignant lesions. The 8579
benign conditions were comprised almost normal stomach in 74 cases (0.9%),
chronic gastritis in 4374 (51.0%), benign gastric peptic ulcer in 2195 (25.6%),
foveolar hyperplastic polyp in 1004 (11.7%), fundic gland polyp in 421 (4.9%),
adenoma in 487 (5.6%), heterotopic pancreas in 9 (0.1%), pancreatic acinar
metaplasia (PAM) in 8 (0.1%), and amyloidosis in 7 (0.1%). Chronic gastritis
showed lymphocytic infiltration and frequently showed erosions and intestinal
metaplasia. Gastric peptic ulcer showed exudate, necrosis, active inflammation,
and regenerative atypia of the epithelium. Foveolar hyperplastic polyp revealed
23 malignant changes and frequently showed dysplastic glands and intestinal
metaplasia. Fundic gland polyp demonstrated cystic dilations of fundic gland
ducts. Gastric adenoma showed adenomatous proliferation in the superficial mucosa
and cystic dilation of the epithelium under the adenoma. Heterotopic pancreas was
located in the submucosa and consisted of acinar cells, ducts, and occasionally
islets. PAM was a tiny lesion in the mucosa and consisted of only pancreatic
acinar cells. Amyloidosis was primary amyloidosis with positive reaction with
Congo-red stain.