Use my Search Websuite to scan PubMed, PMCentral, Journal Hosts and Journal Archives, FullText. Kick-your-searchterm to multiple Engines kick-your-query now !>

A dictionary by aggregated review articles of nephrology, medicine and the life sciences Your one-stop-run pathway from word to the immediate pdf of peer-reviewed on-topic knowledge.

http://scihub22266oqcxt.onion/ C4525850!4525850!26261516     free     free     free Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Int+J+Clin+Exp+Pathol 2015 ; 8 (6): 6407-15 Nephropedia Template TP {{tp|p=26261516|t=2015. Effects of rhBNP on myocardial fibrosis after myocardial infarction in rats |pdf=|usr=}}{{26261516}} gab.com Text Effects of rhBNP on myocardial fibrosis after myocardial infarction in rats JO: Int J Clin Exp Pathol http://www.kidney.de/pget.php?&tw=1&pmid=26261516 #FOAvip Purpose: We aimed to observe the effects and mechanism of rhBNP treatment on myocardial fibrosis (MF) after myocardial infarction (MI). Methods: SPF rats were separated into 3 groups: normal, MI (ligation of left coronary artery), and MI + rhBNP (recombinant human brain natriuretic peptide). Rats in MI + rhBNP group were given 30 ?g/kg for 2 days before modeling and for 4 weeks after modeling. mRNA levels and the expression levels of TGF-?1 (transforming growth factor) and CTGF (connective tissue growth factor) in 3 groups were analyzed using the RT-qPCR and western blotting analysis, respectively. Furthermore, myocardial volume fraction (CVF) was analyzed using the Sirius Red F3B (SR) while the percentage of type I and III collagen in 3 groups were analyzed using the immunohistochemical staining. Results: Compared with the normal group, the levels of TGF-?1, CTGF, CVF, type I and III collagen were higher in MI group. However, mRNA levels of TGF-?1 and CTGF were significantly decreased in MI + rhBNP compared to MI groups. Expression of TGF-?1 was lower while that of CTGF was higher in MI + rhBNP group than that in MI group. Besides, CVF, and type I and III collagen were lower in MI + rhBNP group compared with MI group. Conclusion: rhBNP could significantly decrease the TGF-?1 and CTGF levels in post-MI so as to inhibit the type I and III collagen deposition in MF of post-MI. rhBNP will be benefit for the improvement of MF. Twit Text FOAVip Effects of rhBNP on myocardial fibrosis after myocardial infarction in rats ????Int J Clin Exp Pathol http://www.kidney.de/pget.php?&tw=1&pmid=26261516 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=26261516 #FOAvip English Wikipedia <ref>{{Cite pmid|26261516}}</ref> Effects of rhBNP on myocardial fibrosis after myocardial infarction in rats #MMPMID26261516 Su Z; Wei G; Wei L; Liu J; Li X Int J Clin Exp Pathol 2015[]; 8 (6): 6407-15 PMID26261516show ga Purpose: We aimed to observe the effects and mechanism of rhBNP treatment on myocardial fibrosis (MF) after myocardial infarction (MI). Methods: SPF rats were separated into 3 groups: normal, MI (ligation of left coronary artery), and MI + rhBNP (recombinant human brain natriuretic peptide). Rats in MI + rhBNP group were given 30 ?g/kg for 2 days before modeling and for 4 weeks after modeling. mRNA levels and the expression levels of TGF-?1 (transforming growth factor) and CTGF (connective tissue growth factor) in 3 groups were analyzed using the RT-qPCR and western blotting analysis, respectively. Furthermore, myocardial volume fraction (CVF) was analyzed using the Sirius Red F3B (SR) while the percentage of type I and III collagen in 3 groups were analyzed using the immunohistochemical staining. Results: Compared with the normal group, the levels of TGF-?1, CTGF, CVF, type I and III collagen were higher in MI group. However, mRNA levels of TGF-?1 and CTGF were significantly decreased in MI + rhBNP compared to MI groups. Expression of TGF-?1 was lower while that of CTGF was higher in MI + rhBNP group than that in MI group. Besides, CVF, and type I and III collagen were lower in MI + rhBNP group compared with MI group. Conclusion: rhBNP could significantly decrease the TGF-?1 and CTGF levels in post-MI so as to inhibit the type I and III collagen deposition in MF of post-MI. rhBNP will be benefit for the improvement of MF. äEffects of rhBNP on myocardial fibrosis after myocardial infarction in(epmc).pdf DeepDyve Pubget Overpricing