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http://scihub22266oqcxt.onion/ C4525832!4525832!26261498     free     free     free Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 253.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 253.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 253.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Int+J+Clin+Exp+Pathol 2015 ; 8 (6): 6214-24 Nephropedia Template TP {{tp|p=26261498|t=2015. Mannose prevents acute lung injury through mannose receptor pathway and contributes to regulate PPAR? and TGF-?1 level |pdf=|usr=}}{{26261498}} gab.com Text Mannose prevents acute lung injury through mannose receptor pathway and contributes to regulate PPAR and TGF- 1 level JO: Int J Clin Exp Pathol http://www.kidney.de/pget.php?&tw=1&pmid=26261498 #FOAvip Mannose has been reported to prevent acute lung injury (ALI), and mannose receptor (MR) has been demonstrated to have a role. The rationale for this study is to characterize the mechanism by which mannose and MR prevent lipopolysaccharide (LPS)-induced ALI. Male ICR mice were pretreated mannose by intravenous injection 5 min before and 3 h after intratracheal instillation of LPS. Pathological changes, proinflammatory mediator, peroxisome proliferator activated receptor gamma (PPAR?), MR, and transforming growth factor ?1 (TGF-?1) levels were determined. The RAW264.7 cells were pretreated with mannose and stimulated with LPS for 3 h. Proinflammatory mediator and TGF-?1 in the culture media, PPAR?, MR, and TGF-?1 expression in RAW 264.7 cells were measured. Mannose markedly attenuated the LPS-induced histological alterations and inhibited the production of proinflammatory mediator in mice and in RAW 264.7 cells. Mannose increased PPAR? and MR expression, and inhibited TGF-?1 stimulated by LPS. Interestingly, competitive inhibition of MR with mannan was associated with elimination of the anti-inflammatory effects of mannose, and reversed effects of mannose of regulation to PPAR? and TGF-?1. MR is important in increasing PPAR? and decreasing TGF-?1 expression and plays a critical role in mannose?s protection against ALI. Twit Text FOAVip Mannose prevents acute lung injury through mannose receptor pathway and contributes to regulate PPAR and TGF- 1 level ????Int J Clin Exp Pathol http://www.kidney.de/pget.php?&tw=1&pmid=26261498 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=26261498 #FOAvip English Wikipedia <ref>{{Cite pmid|26261498}}</ref> Mannose prevents acute lung injury through mannose receptor pathway and contributes to regulate PPAR? and TGF-?1 level #MMPMID26261498 Xu XL; Zhang P; Shen YH; Li HQ; Wang YH; Lu GH; Zhou JY Int J Clin Exp Pathol 2015[]; 8 (6): 6214-24 PMID26261498show ga Mannose has been reported to prevent acute lung injury (ALI), and mannose receptor (MR) has been demonstrated to have a role. The rationale for this study is to characterize the mechanism by which mannose and MR prevent lipopolysaccharide (LPS)-induced ALI. Male ICR mice were pretreated mannose by intravenous injection 5 min before and 3 h after intratracheal instillation of LPS. Pathological changes, proinflammatory mediator, peroxisome proliferator activated receptor gamma (PPAR?), MR, and transforming growth factor ?1 (TGF-?1) levels were determined. The RAW264.7 cells were pretreated with mannose and stimulated with LPS for 3 h. Proinflammatory mediator and TGF-?1 in the culture media, PPAR?, MR, and TGF-?1 expression in RAW 264.7 cells were measured. Mannose markedly attenuated the LPS-induced histological alterations and inhibited the production of proinflammatory mediator in mice and in RAW 264.7 cells. Mannose increased PPAR? and MR expression, and inhibited TGF-?1 stimulated by LPS. Interestingly, competitive inhibition of MR with mannan was associated with elimination of the anti-inflammatory effects of mannose, and reversed effects of mannose of regulation to PPAR? and TGF-?1. MR is important in increasing PPAR? and decreasing TGF-?1 expression and plays a critical role in mannose?s protection against ALI. äMannose prevents acute lung injury through mannose receptor pathway an(epmc).pdf DeepDyve Pubget Overpricing